|本期目录/Table of Contents|

[1]魏佳,韩娟综述,颜浩审校.晚期糖基化终末产物受体与肺部疾病研究进展[J].医学研究与战创伤救治(原医学研究生学报),2019,21(3):291-296.[doi:10.3969/j.issn.1672-271X.2019.03.015]
　WEI Jia,HAN Juan reviewing,YAN Hao checking.Progress of receptor for advanced glycation end products and pulmonary disease[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2019,21(3):291-296.[doi:10.3969/j.issn.1672-271X.2019.03.015]
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晚期糖基化终末产物受体与肺部疾病研究进展()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第21卷
期数:
2019年3期
页码:
291-296
栏目:
综述
出版日期:
2019-05-10

文章信息/Info

Title:
Progress of receptor for advanced glycation end products and pulmonary disease
文章编号:
1672-271X（2019）03-0291-06
作者:
魏佳;  韩娟综述;  颜浩审校
作者单位：610017 成都，成都市第二人民医院呼吸与危重症医学一科(魏 佳、韩 娟、颜 浩)
Author(s):
WEI Jia;  HAN Juan reviewing;  YAN Hao checking
(Department of Respiratory and Critical Care Medicine, Chengdu Second People’s Hospital, Chengdu 610017, Sichuan, China)
关键词:
晚期糖基化终末产物受体;  可溶性晚期糖基化终产物受体;  肺部疾病
Keywords:
receptor for advanced glycation end products;  soluble RAGE;  pulmonary disease
分类号:
R563
DOI:
10.3969/j.issn.1672-271X.2019.03.015
文献标志码:
A
摘要:
晚期糖基化终末产物受体（RAGE）是细胞表面免疫球蛋白超家族成员之一，在人体多种细胞内广泛表达。哮喘、慢性阻塞性肺疾病(COPD)等肺部疾病发病率及死亡率高，与RAGE联系相关。文章主要就RAGE在哮喘、囊性肺纤维化、急性呼吸窘迫综合征、支气管肺发育不良、间质性肺疾病、肺癌以及COPD等肺部疾病中的研究进展进行综述。
Abstract:
Receptor for advanced glycation end products（RAGE）is one of the multi-ligand members of the immunoglobulin superfamily of cell surface molecules. It is widely expressed in human endothelial cells, smooth muscle cells, mesangial cells, mononuclear macrophages and neurons. Pulmonary diseases such as asthma and chronic obstructive pulmonary disease (COPD) have high morbidity and mortality which are closely associated with RAGE. The biology of RAGE and research progress of RAGE in pulmonary diseases such as asthma, cystic fibrosis, acute respiratory distress syndrome, bronchopulmonary dysplasia, interstitial lung disease, lung cancer and COPD are described in this review for a new direction for future research.

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相似文献/References:

[1]庄 微综述,刘挺松审校.晚期糖基化终末产物受体在心血管疾病中的研究概况[J].医学研究与战创伤救治(原医学研究生学报),2014,16(06):629.[doi:10.3969/j.issn.1672-271X.2014.06.021]

备注/Memo

备注/Memo:
收稿日期：2018-09-17
更新日期/Last Update: 2019-05-10