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[1]祝小欢,俞冠东.阴道混合感染患者阴道菌群分布特征及感染相关危险因素分析[J].医学研究与战创伤救治(原医学研究生学报),2019,21(4):365-368.[doi:10.3969/j.issn.1672-271X.2019.04.007]
　ZHU Xiao-huan,YU Guan-dong.Distribution characteristics and risk factors of vaginal flora in patients with mixed vaginal infection[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2019,21(4):365-368.[doi:10.3969/j.issn.1672-271X.2019.04.007]
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阴道混合感染患者阴道菌群分布特征及感染相关危险因素分析()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第21卷
期数:
2019年4期
页码:
365-368
栏目:
临床研究
出版日期:
2019-07-20

文章信息/Info

Title:
Distribution characteristics and risk factors of vaginal flora in patients with mixed vaginal infection
文章编号:
1672-271X（2019）04-0365-04
作者:
祝小欢; 俞冠东
作者单位：330001南昌，解放军联勤保障部队第九○八医院体检中心（祝小欢、俞冠东）
Author(s):
ZHU Xiao-huan;  YU Guan-dong
(Department of Physical Examination，the 908th Hospital of the Joint Logistics Support Force，PLA，Nanchang 330001，Jiangxi，China)
关键词:
阴道炎;  阴道菌群;  混合感染;  分布特征;  危险因素
Keywords:
vaginitis;  vaginal flora;  mixed infection;  distribution characteristics;  risk factors
分类号:
R711.31
DOI:
10.3969/j.issn.1672-271X.2019.04.007
文献标志码:
A
摘要:
目的 分析阴道混合感染者的阴道菌群分布特征及引起感染的相关危险因素，为防治女性阴道感染提供指导意见。 方法 回顾性分析2016年8月至2018年2月在解放军联勤保障部队第九○八医院门诊就诊的阴道炎患者401例的临床资料，收集患者阴道分泌物生态检测和真菌、细菌培养鉴定以及支原体检测的结果，根据检测结果记录患者阴道感染情况及相关感染类型，记录患者年龄、清洁度分级、流产次数、初次性交年龄等临床资料，通过Logistic分析影响阴道混合感染的危险因素。 结果 401例阴道炎患者中单一感染者94例（23.44%），其中细菌性阴道炎（BV）感染者最多，占比6.98%；其次为生殖道支原体（MP）感染，占比6.48%。混合感染者167例（41.65%），其中需氧菌性阴道炎（AV）+BV+MP感染者最多，占比18.20%；其次为BV+MP感染，占比9.23%。菌群失调140例（34.91%）。单因素分析结果显示：混合感染与年龄、文化程度、清洁度分级、流产次数、初次性交年龄、分娩次数、性伴侣个数及避孕套使用情况有关（P<0.05）；Logistic分析结果显示：年龄、清洁度、流产次数、分娩次数、性伴侣个数、未使用避孕套均为引起阴道混合感染的独立危险因素（P<0.01）；而初次性交年龄≥22岁则为阴道混合感染的保护因素（P<0.01）。 结论 混合感染中以AV+BV+MP感染较为常见，且阴道混合感染的发生与育龄女性、清洁度过高、流产与分娩次数多、多个性伴侣及不使用避孕套有关，临床可通过女性健康知识宣教、定期进行阴道感染筛查及改善阴道内微环境等方式防治阴道混合感染。
Abstract:
Objective To provide guidance for the prevention and treatment of vaginal infection，the distribution characteristics of vaginal flora and the related risk factors were analyzed. Methods 401 cases of vaginitis in 908 Hospital of the Joint Service of the Chinese people’s Liberation Army from August 2016 to February 2018 were enrolled.Collection of vaginal secretions for ecological detection，fungi，bacteria culture identification and mycoplasma detection. According to the test results，the vaginal infection and related infection types were recorded，and the clinical data including age，cleanliness grade，abortion frequency，age of first sexual intercourse were recorded. Risk factors for mixed vaginal infection were analyzed by logistic. Results 94 cases (23.44%) were infected by single bacteria，among which bacterial infection and mycoplasma genitalis (MP)accounted for 6.98%, and 6.48%, respectively. In 167 cases (41.65%) of mixed infection， the Aerobic vaginitis(AV)+ BV+ MP infection accounted for 18.20%, BV+ MP infection was 9.23%. 140 cases (34.91%) were dysbacteriosis. Univariate analysis showed that mixed infection was associated with age，education，cleanliness，abortion，age of the first sexual intercourse，number of delivery，number of sexual partners and condom use (all P<0.05). Logistic analysis showed that age，cleanliness，number of abortions，number of births，number of sexual partners and no condom use were independent risk factors for mixed vaginal infection (P<0.01). The age of first sexual intercourse≥22 years old was the protective factor of vaginal mixed infection (P<0.01). Conclusion In the mixed infection，AV BV MP infection was more common，and vaginal mixed infection was associated with reproductive age women，too clean degree，abortion and delivery times，number of sexual partners，not using condoms. Women’s health education，regular screening of vaginal infection and improvement of microenvironment in vagina can be used to prevent and control mixed vaginal infection.

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备注/Memo

备注/Memo:
收稿日期：2018-09-11
更新日期/Last Update: 2019-07-11