|本期目录/Table of Contents|

[1]梁弦弦,刘丽,许健.CT引导下经皮肝穿刺活检在肝占位性病变的应用价值[J].医学研究与战创伤救治(原医学研究生学报),2021,23(03):271-275.[doi:10.3969/j.issn.1672-271X.2021.03.011]
　LIANG Xian-xian,LIU Li,XU Jian.Clinical application of CT-guided percutaneous liver biopsy in hepatic space-occupying lesions[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(03):271-275.[doi:10.3969/j.issn.1672-271X.2021.03.011]
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CT引导下经皮肝穿刺活检在肝占位性病变的应用价值()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年03期
页码:
271-275
栏目:
临床研究
出版日期:
2021-06-20

文章信息/Info

Title:
Clinical application of CT-guided percutaneous liver biopsy in hepatic space-occupying lesions
作者:
梁弦弦; 刘丽; 许健
作者单位：221004徐州，徐州医科大学医学影像学院（梁弦弦、许健）；210002南京,东部战区总医院（原南京军区南京总医院）介入治疗科（刘丽）
Author(s):
LIANG Xian-xian;  LIU Li;  XU Jian
(1.Medical Imaging College, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China; 2.Department of Interventional Therapy, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu, China)
关键词:
肝占位; 经皮肝穿刺活检; CT引导; 诊断准确率; 并发症; 危险因素
Keywords:
hepatic space-occupying lesion;  percutaneous liver biopsy;  CT-guided;  diagnostic accuracy;  complication;  risk factor
分类号:
R446.8
DOI:
10.3969/j.issn.1672-271X.2021.03.011
文献标志码:
A
摘要:
目的探讨CT引导下经皮肝穿刺活检在肝占位性病变中的应用价值和安全性。方法回顾性分析东部战区总医院介入治疗科2016年至2019年行CT引导下经皮肝穿刺活检的510例肝占位性病变患者的临床资料，分析CT引导下经皮肝穿刺活检术的诊断准确率和并发症的危险因素。结果CT引导下经皮肝穿刺活检的技术成功率100%，病理诊断准确率95.5%（487/510），其中良性病变诊断准确率94.4%（51/54），恶性病变诊断准确率95.6%（436/456），恶性病变诊断灵敏度95.6%（436/456），特异度100%（51/51）。CT引导下经皮肝穿刺活检术后并发症发生率4.5%（23/510），其中疼痛发生率3.1%（16/510），出血发生率1% (5/510)，胆管积气发生率0.4%（2/510）。单因素分析显示并发症与性别、年龄及取材次数之间差异有统计学意义（P＜0.05）。多因素Logistic回归分析提示女性、年龄≤50岁、取材次数＞2次及血小板计数≤60×109/L是并发症的危险因素。结论CT引导经皮肝穿刺活检在肝占位病变中具有较高的诊断灵敏度和特异度，有助于提高恶性病变的诊断准确性，同时具有可接受的较低的并发症发生率。
Abstract:
ObjectiveTo evaluate the value and safety of CT-guided percutaneous liver biopsy in hepatic space-occupying lesions.MethodsThe clinical data of 510 patients with hepatic space-occupying lesions, who received CT-guided percutaneous liver biopsy from 2016 to 2019, were retrospectively analyzed. The diagnostic accuracy and risk factors of complications were analyzed.ResultsThe technical success rate of CT-guided percutaneous liver biopsy was 100%. The accuracy of pathological diagnosis was 95.5% (487/510). The diagnostic accuracy of benign lesions was 94.4% (51/54). The diagnostic accuracy of malignant lesions was 95.6% (436/456). The sensitivity of malignant lesions was 95.6% (436/456).The specificity was 100% (51/51). The incidence of complications of CT-guided percutaneous liver biopsy was 4.5% (23/510), including pain (3.1%, 16/510), bleeding (1%, 5/510) and the gas accumulation in bile duct (0.4%, 2/510). The chi-square test showed that there were significant differences between complications and sex, age and times of sampling (P＜0.05). Logistic regression analysis showed that female, age ≤ 50 years old, sampling times >2 times and platelet count ≤ 60×109/L were the risk factors of complications.ConclusionCT-guided percutaneous liver biopsy has high diagnostic sensitivity and specificity in liver occupying lesions, which improves the diagnostic accuracy of malignantlesions, and has an acceptable low rate of complications.

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更新日期/Last Update: 2021-06-17