|本期目录/Table of Contents|

[1]刘海鹏,刘小微,朱峰,等.儿童肾性急性肾损伤病理分型与预后分析[J].医学研究与战创伤救治(原医学研究生学报),2022,24(1):40-44.[doi:10.3969/j.issn.1672-271X.2022.01.009]
　LIU Hai-peng,LIU Xiao-wei,ZHU Feng,et al.Analysis of pathological classification and prognosis of children with renal-acute kidney injury[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2022,24(1):40-44.[doi:10.3969/j.issn.1672-271X.2022.01.009]
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儿童肾性急性肾损伤病理分型与预后分析()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第24卷
期数:
2022年1期
页码:
40-44
栏目:
临床研究
出版日期:
2022-02-20

文章信息/Info

Title:
Analysis of pathological classification and prognosis of children with renal-acute kidney injury
作者:
刘海鹏; 刘小微; 朱峰; 祁伯祥
作者单位：221000徐州，徐州医科大学附属徐州儿童医院急诊科（刘海鹏、朱峰、祁伯祥）；221000徐州，徐州市传染病医院重症医学科（刘小微）
Author(s):
LIU Hai-peng;  LIU Xiao-wei;  ZHU Feng;  QI Bo-xiang
(1.Department of Emergency, Xuzhou Children’s Hospital Affiliated to Xuzhou Medical University, Xuzhou 221000, Jiangsu, China; 2.Department of Critical Care Medicine, Xuzhou Infectious Diseases Hospital, Xuzhou 221000, Jiangsu, China)
关键词:
急性肾损伤; 儿童; 病理; 预后
Keywords:
acute renal injury; children; pathology; prognosis
分类号:
R726.9
DOI:
10.3969/j.issn.1672-271X.2022.01.009
文献标志码:
A
摘要:
目的探讨儿童肾性急性肾损伤的病理分型和预后因素。方法回顾性分析183例肾性急性肾损伤患儿临床特征、急性肾损伤分级、肾脏病理分型和预后，分析肾脏病理分型和预后的关系。结果入组患儿以学龄期和学龄前期为主；病理分型以急性肾小球肾炎(AGN)、急进性肾小球肾炎(RPGN)、系膜增生性肾小球肾炎(MsPGN)和血栓性微血管病(TMA)为主；急性肾损伤分级以3期为主；总体治愈率为88.52%，好转率为7.65%，未愈率为2.73%，死亡率为1.09%；AGN、特发性膜性肾病(IMN)和紫癜性肾炎(HSPN)的治愈率为100%；其次为微小病变(MCD)（93.33%）、IgA肾病(IgAN)（90.91%）、狼疮性肾炎(LN)（88.89%）、TMA（88.89%）、MsPGN（84.21%）、膜增生性肾小球肾炎(MPGN)（81.82%）、局灶节段性肾小球硬化(FSGS)（80.00%）和RPGN（68.97%）；RPGN和TMA各有1例死亡。结论不同病理表现的儿童急性肾损伤的分级、临床表现和预后不一，早期发现和规范化治疗是降低死亡率的重要措施。
Abstract:
ObjectiveTo investigate the pathological classification and prognostic factors of renal-acute renal injury in children (R-AKI).MethodsThe clinical features, grade of AKI, renal pathological classification and prognosis of 183 children with R-AKI were analyzed retrospectively, and the relationship between renal pathological and prognosis was analyzed.ResultsAll cases were mainly included in school age and pre-school age. AGN, RPGN, MsPGN and TMA were the main pathological types, and the grade of AKI was mainly in stage 3. The overall cure rate was 88.52%, the improvement rate was 7.65%, the uncured rate was 2.73%, and the mortality rate was 1.09%. The cure rate of AGN, IMN and HSPN was 100%, followed by MCD (93.33%), IgAN (90.91%), LN (88.89%), TMA (88.89%), MsPGN (84.21%), MPGN (81.82%), FSGS (80.00%) and RPGN (68.97%). There was each case with RPGN and TMA died.ConclusionThe AKI grade, clinical manifestation and prognosis of AKI with different pathological manifestations are different. Early detection and standardized treatment are important measures to reduce mortality of AKI.

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更新日期/Last Update: 2022-02-21