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[1]殷晓颖,吴曼,吴腾珍,等.超声引导下聚桂醇与无水乙醇介入治疗卵巢囊肿的效果比较[J].医学研究与战创伤救治(原医学研究生学报),2022,24(3):262-266.[doi:10.3969/j.issn.1672-271X.2022.03.008]
　YIN Xiao-ying,WU Man,WU Teng-zhen,et al.Comparison of clinical efficacy of ultrasound-guided sclerotherapy for ovarian cysts using lauromacrogol and anhydrous ethanol injections[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2022,24(3):262-266.[doi:10.3969/j.issn.1672-271X.2022.03.008]
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超声引导下聚桂醇与无水乙醇介入治疗卵巢囊肿的效果比较()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第24卷
期数:
2022年3期
页码:
262-266
栏目:
临床研究
出版日期:
2022-06-30

文章信息/Info

Title:
Comparison of clinical efficacy of ultrasound-guided sclerotherapy for ovarian cysts using lauromacrogol and anhydrous ethanol injections
作者:
殷晓颖; 吴曼; 吴腾珍; 肖梅; 税迎春
作者单位：210002南京，东部战区总医院（原南京军区南京总医院）妇产科（殷晓颖、吴曼、吴腾珍、肖梅、税迎春）
Author(s):
YIN Xiao-ying; WU Man;  WU Teng-zhen;  XIAO Mei;  SHUI Ying-chun
（Department of Obstetrics and Gynecology, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu, China）
关键词:
超声引导; 聚桂醇; 无水乙醇; 卵巢囊肿
Keywords:
ultrasound-guided;  lauromacrogol;  anhydrous ethanol;  ovarian cysts
分类号:
R711.75
DOI:
10.3969/j.issn.1672-271X.2022.03.008
文献标志码:
A
摘要:
目的比较超声引导下聚桂醇与无水乙醇介入治疗卵巢囊肿的疗效。方法回顾性分析2015年1月至2017年12月间在东部战区总医院进行治疗的80例卵巢囊肿患者的临床资料，根据术中囊腔内注入硬化剂不同分为聚桂醇组（40例）和无水乙醇组（40例）。统计2组手术时间，运用视觉模拟评分法（VAS）评估患者术后疼痛，比较2组治疗效果，术后3、6、12个月复查B超进行随访，分析比较2组远期疗效。结果聚桂醇组平均手术时间、平均住院时间、腹痛VAS评分分别为（25.25±6.55）min、（3.62±0.73）d和（1.32±1.25）分，均显著低于无水乙醇组[（46.78±15.17）min、（4.26±0.85）d和（3.24±1.72）分]，差异有统计学意义（P<0.01）。聚桂醇组发热反应例数（3例）、醉酒反应例数（0例）、囊内出血例数（2例）显著低于无水乙醇组（10例、6例、8例），差异有统计学意义（P<0.05）；术后3、6、12个月聚桂醇组临床总有效率分别为97.5%、90.0%和82.5%，无水乙醇组分别为100.0%、95.0%和85.0%，聚桂醇组略低于无水乙醇组，差异无统计学意义（P>0.05）。结论超声引导下聚桂醇介入治疗卵巢囊肿的效果与无水乙醇比较无明显差别，但聚桂醇介入治疗在手术时间、术后并发症方面优于无水乙醇。
Abstract:
ObjectiveTo compare and analyze the clinical efficacy of sclerotherapy for ovarian cysts using lauromacrogol and anhydrous ethanol injections under the guidance of ultrasound.MethodsThe clinical data of 80 patients with ovarian cyst treated in the General Hospital of Eastern Theater Command, PLA from January 2015 to December 2017 were retrospectively analyzed. According to the intraoperative injection of sclerosing agent, they were divided into lauryl alcohol group (40 cases) and absolute ethanol group (40 cases). The therapeutic effects including visual analogue scale/Score (VAS), operation time and adverse reactions were recorded and compared between the two groups. At the 3rd, 6th, 12th months after operation, the B-ultrasound and follow up were performed to compare the long-term effects of the two groups.ResultsThe operation time, average hospital days and VAS score in lauromacrogol group were (25.25±6.55)min, (3.62±0.73)d and (1.32±1.25), respectively. Those values of anhydrous ethanol group were (46.78±15.17)min, (4.26±0.85)d and (3.24±1.72), respectively. The values of polycinnamic alcohol group were significantly lower than that in anhydrous alcohol group (P<0.01). Patients with fever reaction (3 cases), drunk response (0 cases) and intracapsular hemorrhage (2 cases) in the anhydrous ethanol group were significantly lower than the lauromacrogol group (10 cases/6 cases/8 cases) (P<0.05). At the 3rd, 6th, 12th month after surgery, the total clinical effective rate in the lauromacrogol group was 97.5%, 90.0%, and 82.5%, respectively. Whereas the total clinical effective rate in the anhydrous ethanol group was 100.0%, 95.0%, and 85.0%, the values of polycinnamyl alcohol group and anhydrous alcohol group were not statistically significant (P>0.05).ConclusionThere is no significant difference in the effect of ultrasound-guided lauromacrogol intervention in the treatment of ovarian cysts compared with anhydrous ethanol, but ultrasound-guided lauromacrogol intervention is superior to anhydrous ethanol in terms of surgical time and postoperative complications.

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更新日期/Last Update: 2022-06-21