|本期目录/Table of Contents|

[1]王 坚,郝立校,焦成文,等.胆管内用药预防内镜下胰胆管逆行造影[J].医学研究与战创伤救治(原医学研究生学报),2009,11(01):17-19.
　WANG Jian,HAO Li-xiao,JIAO Cheng-wen,et al.Injection of medicines in the bile duct to prevent the acute pancreatitis in the ERCP[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2009,11(01):17-19.
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第11卷
期数:
2009年01期
页码:
17-19
栏目:
出版日期:
2009-01-20

文章信息/Info

Title:
Injection of medicines in the bile duct to prevent the acute pancreatitis in the ERCP
作者:
王 坚1 ; 郝立校1; 焦成文1; 皋岚雅1; 王惠菊1; 丁新峰1; 蔡珍福1; 顾树南2
1.解放军第455医院肝胆外科，上海 200052；2.兰州军区总医院普外科，甘肃兰州 730050
Author(s):
WANG Jian1; HAO Li-xiao1;  JIAO Cheng-wen1;  GAO Lan-ya1; WANG Hui-ju1; DING Xin-feng1; CAI Zhen-fu1; GU Shu-nan2
1.Department of Hepatobiliary Surgery,the 455th Hospital of PLA, Shanghai 200052,China;2.Department of General Surgery,Lanzhou General Hospital of Lanzhou Military Command,Lanzhou 730050,Gansu,China
关键词:
内镜下胰胆管逆行造影; 急性胰腺炎; 山莨菪碱; 庆大霉素
Keywords:
ERCP;  Acute pancreatitis;  Anisodamine;  Gentamycin
分类号:
R657.5
DOI:
-
文献标志码:
A
摘要:
目的 探讨胆管内用药对预防内镜下胰胆管逆行造影(ERCP)后出现高淀粉酶血症及急性胰腺炎的效果。方法 在1 100例ERCP患者操作中，通过胆管内直接注入氢溴酸山莨菪碱、硫酸庆大霉素，观察操作后3小时、16小时血淀粉酶的升高程度，随机对比452例非胆管内用药患者，并采用医学统计方法，分析用药组与非用药组患者血淀粉酶变化的显著性意义(χ2检验)。结果 治疗组血淀粉酶的升高频次及程度，明显低于对照组(术后3小时血淀粉酶升高在治疗组中有325例，占29.5%，对照组有288例，占63.7%，χ2值为156.63；术后16小时血淀粉酶升高在治疗组中有218例，占19.8%，对照组有263例，占58.2%，χ2值为1 409.52)。结论 ERCP患者在操作中胆管内注入氢溴酸山莨菪碱、硫酸庆大霉素，能够明显降低ERCP后患者的高淀粉酶血症及急性胰腺炎的发病率。
Abstract:
Objective To explore the effectiveness of injecting medicines to the bile duct in the prevention of the hyperamylasemia and the acute pancreatitis after the endoscopic retrograde cholangio pancreatography (ERCP). Methods In 1 100 cases of the patients subjected to ERCP，after injecting the anisodamine and gentamycin to the bile duct for 3 hours and 16 hours, the level of the amylase in blood were checked. The data were compared with that from 452 patients without using medicine in the bile duct. The alteration of hemodiastase levels before and after using medicines was analyzed using a chi-square test. Results The frequency and level of the amylase in the treatment group were obviously lower than that in the contrast group. The blood amylase of 325 cases (29.5%) in the treatment group were increased 3 hours after ERCP, and 288 cases (63.7%) in the control group increased (χ2 value was 156.63). The blood amylase in the treatment group 16 hours after ERCP was increased in 218 cases (19.8%) and the control group had 263 cases (58.2%, χ2 value was 1 409.52). Conclusion Injection of the 654-2 and gentamycin to the bile duct in patients subjected to ERCP can decrease the incidence of hyperamylasemia and acute pancreatitis.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2013-11-20