|本期目录/Table of Contents|

[1]于晓莉,赵丽文,张烨敏.黄体中期血清孕酮测定和子宫内膜活检在不孕症诊断中的意义[J].医学研究与战创伤救治(原医学研究生学报),2010,12(05):401-403.
　YU Xiao-li,ZHAO Li-weng,ZHANG Ye-min..The significance of progesterone profile and endometrial biopsy during luteal median phase in diagnosis of infertile women[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2010,12(05):401-403.
点击复制

黄体中期血清孕酮测定和子宫内膜活检在不孕症诊断中的意义()
分享到62.8K

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第12卷
期数:
2010年05期
页码:
401-403
栏目:
出版日期:
2010-09-20

文章信息/Info

Title:
The significance of progesterone profile and endometrial biopsy during luteal median phase in diagnosis of infertile women
文章编号:
1672-271X(2010)05-0401-03
作者:
于晓莉1; 赵丽文2; 张烨敏1
1.210052 上海，解放军85医院妇产科；2.361000 福建厦门，解放军174医院妇产科
Author(s):
YU Xiao-li1; ZHAO Li-weng2 ;  ZHANG Ye-min1.
1.Department of Obstetrics and Gynecology,85 Hospital of PLA,Shanghai,200052,China；2. Department of Obstetrics and Gynecology,174 Hospital of PLA，Xiamen,361000,China
关键词:
黄体中期; 子宫内膜; 孕激素; 不孕症
Keywords:
luteal phase;  endometorium; progesterone;  infertility
分类号:
R711.6
DOI:
-
文献标志码:
A
摘要:
目的 对原因不明不孕症患者的黄体中期行血清孕酮测定和子宫内膜活检，寻找不孕的原因及其在诊断中的意义。方法 对58例不孕症患者黄体中期(排卵后第7天)检测血清孕酮水平，同时取子宫内膜病理检查。结果 58例不孕症患者中黄体中期分泌延迟46例，分泌正常12例(P﹤0.01)。血清孕酮水平﹤47.7 nmol/L 30例，≥47.7 nmol/L 28例(P﹤0.05)。在分泌延迟的46例不孕症患者中，60.87%黄体中期血清孕酮水平﹤47.7 nmol/L ，39.13%≥47.7 nmol/L (P﹤0.01)。结论 黄体中期行血清孕酮测定和子宫内膜活检更易发现患者不孕的原因。对于不孕症的诊断和指导治疗具有重要的意义。
Abstract:
Objective To investigate the significance of progesterone profile and endometrial biopsy during luteal median phase in diagnosis of infertile women. Methods The progesterone profiles during median luteal phase and endometrial histology during median luteal phase in 58 infertile women were studied. The biopsy of endometrium was carried out as well. Results Retarded endometrial development occurred in the median luteal phase in 46 of the 58 cases (P﹤0.01).The progesterone profile of these patients was markedly lower compared with the control group (P﹤0.05). Conclusion The progesterone profile during median luteal phase and endometrial biopsy during median luteal phase can judge infertile reasons, and has an important significance for diagnosis and treatment.

参考文献/References:

[1]李艳君.B超监测卵泡发育与排卵在不孕症中的临床应用[J].中国实用医药,2009,4(7):7-8.
[2]于传鑫，李诵炫.实用妇科内分泌学[M].2版.上海:复旦大学出版社,2006:176-178.
[3]戴 琳，沈 浣，王一丁,等.不孕症患者子宫内膜孕激素受体研究[J].中华病理学杂志,2000,29(3):184-187.
[4]Noyes RW, Hertig AT,Rock J. Dating the endometrial biopsy[J].Fertil Steri,1950,1(1):3-5.
[5]张 媛.黄体功能不全患者着床期子宫内膜整合素β3的表达及超微结构改变[J].华中科技大学学报:医学版,2009,38(4):473-476.
[6]赵明辉，雷呈志，韩佩珍,等.瘦素在黄体功能不足患者子宫内膜中的表达[J].生物医学工程与临床,2005,9(2):103-104.
[7]沈 浣，王一丁，戴 琳,等.有排卵型不孕患者种植窗时期与经前期子宫内膜分泌改变不一致现象及临床意义[J].中国计划生育学杂志,2001,9(2):85-87.
[8]Usadi RS,Murray MJ,Bagnell RC, et al.Temporal and morphologic characteristics of pinopod expression across the secretory phase of the endometrial cycle in normally cycling women with proven fertility[J].Fertil Steril,2004,79(4):970-974.
[9]杜 惠，崔和春，李静波,等.黄体期缺陷与原因不明不孕症关系初探[J].中国妇幼保健,2004,19(9):72-73.
[10]马 珏，李 路，高晓红,等.种植窗期人子宫内膜组织SDF-1а/CXCR4的表达[J].上海交通大学学报:医学版,2010,30(3):305-309.
[11]戴辉华,张红梅，刘嘉茵,等.不孕症患者种植窗期子宫内膜中L-选择素配体合成酶的表达及意义[J].中国实用妇科与产科杂志,2006,22(9):688-690.
[12]Bulletti C,Flamigni C,de Ziegler D. lmplantation markers and endometriosis [J].Reprod Biomed Online,2005,11(4):464-468.
[13]Karahan N,Guney M,Baspinar S,et al.Expression of gelatinase (MMP-2 and MMP-9)and cyclooxygenase -2 (COX-2)in endometrial carcinoma[J].Eur J Gynaecol Oncol,2007,28(3):184-188.
[14]戴 琳, 王一丁，沈 浣,等.黄体中期子宫内膜活检在诊断黄体功能中的意义[J].中华病理学杂志,1999,28(5):344.
[15]童庆红.200例不孕症患者子宫内膜的病理检查分析[J].浙江临床医学,2009,11(6):633-634.
[16]周世英.不孕症患者子宫内膜雌孕激素受体含量变化[J].山东医药,2006,46(7):17.
[17]汪宏波,占海英，李红发,等.黄体功能不全患者着床期子宫内膜雌孕激素受体的表达及超微结构改变[J].中国妇幼保健,2004,19(6):44-46.
[18]沈 浣，罗福兰，田 莉,等.超声监测卵泡发育对自然流产患者的病因学诊断及治疗意义[J].中国超声医学杂志,2003,19(12):939-941.
[19]庞厚清,韩字研，何 敏,等.原发不孕与继发不孕超声监测排卵结果对比分析[J].实用妇产科杂志,2009,25(1):32-34.
[20]宣银风.超声监测卵泡发育对自然流产的病因学诊断及指导治疗的意义[J].实用医学影像杂志,2009,10(4):255-257.

相似文献/References:

[1]王小红,王军青,王志君,等.射频消融子宫内膜治疗围绝经期功能失调性子宫出血的临床研究[J].医学研究与战创伤救治(原医学研究生学报),2012,14(01):64.

备注/Memo

备注/Memo:
-
更新日期/Last Update: 2010-09-20