|本期目录/Table of Contents|

[1]曾 明,赵维娟,甘 静,等.舒通胶囊提取工艺的优选[J].医学研究与战创伤救治(原医学研究生学报),2011,13(02):133.
　ZENG Ming,ZHAO Wei-juan,GAN Jing,et al.Study on the extraction process of Shutong capsules[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(02):133.
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舒通胶囊提取工艺的优选()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年02期
页码:
133
栏目:
出版日期:
2011-03-20

文章信息/Info

Title:
Study on the extraction process of Shutong capsules
文章编号:
1672-271X(2011)02-0133-03
作者:
曾 明; 赵维娟; 甘 静; 陈 艳
100700 北京，北京军区总医院药理科
Author(s):
ZENG Ming;  ZHAO Wei-juan;  GAN Jing;  CHEN Yan
The Pharmacology Department of Beijing Military Command General Hospital, Beijing 100700, China
关键词:
舒通胶囊; 正交实验; 柚皮苷; 浸膏量
Keywords:
Shutong capsules;  orthogonal test;  naringin;  extract
分类号:
R581.1
DOI:
-
文献标志码:
A
摘要:
目的 优选舒通胶囊的最佳提取工艺。方法 采用正交设计法，以浸膏量及高效液相色谱法测定柚皮苷的含量，筛选出舒通胶囊的优化提取条件。结果 最佳提取工艺为10倍量水煎煮提取2次，每次1 h。结论 该提取工艺稳定性、重复性好，为该制剂的生产提供了实验依据。
Abstract:
Objective To optimize the process of the Shutong capsules. Methods The orthogonal test was employed for selecting the optimum of the extraction technology to screen out the best extraction process by measuring the contents of naringin and the evaluation of extracts. Results The best extraction process includes 10 times volume of water for boiling for 2 times, each time for 1h. Conclusion This method is stable, replicable and feasible, and can be used for industrial production.

参考文献/References:

[1]杨武亮，陈海芳，佘金宝，等.枳壳活性化学成分研究[J]. 中药材，2008，31(12):1812-1815.
[2]Zhou DY, Xu Q, Xue XY, et al.characterization of polymethoxylated flavones in Fructus aurantii by off-line two-dimensional liqid chromatogarapy/electrospray ionization-ion trap mass spectrometry [J]. J Pharm Biomed Anal, 2009,49(2):207-213.
[3]Si PY, He Q, Song Y, et al. Characterization and identiflcation of isomeric flavonoid O-dinglycosiders from genus Citrus in negative electrospray ionization by iontrap mass spectrometry [J]. Anal Chim Acta, 2007, 598(1):110-118.
[4]Zhou DY, Xu Q, Xue XY, et al. Rapid qualitative and quantitative analyses of flavanone aglycones in Fructus aurantii by HPLC ion-trap MS[J]. J Sep Sci, 2007,598(1):858-867.
[5]Fang TZ, Wang YG, Ma Y, et al.A rapid LC/MS/MS quantitation assay for naringin and its two metabolites in rats plasma [J]. J Pharm Biomed Anal, 2006,40(2):454-459.
[6]马超一，高温远，高 颖，等. 枳壳化学成分和代谢成分的UPLC-PAD-Q-TOF/MA分析[J]. 药物评价研究，2010，33(2):110-115.
[7]国家药典委员会.中华人民共和国药典一部[S].北京:化学工业出版社，2005:171-172.
[8]陈 艳，许 茜，许景峰，等. 正交设计优化姜香脐贴中木香醇提工艺[J]. 东南国防医药，2010，12(1):39-40.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2011-03-20