|本期目录/Table of Contents|

[1]林 杰,陈力平,肖 立,等.同型半胱氨酸、C反应蛋白与血脂相关指标对冠心病诊断的比较[J].医学研究与战创伤救治(原医学研究生学报),2011,13(06):509-511.
　LIN Jie,CHEN Li-ping,XIAO Li,et al.Evaluation of serum homocysteine,C-reactive protein and various lipid lipoprotein in diagnosis of coronary heart disease[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(06):509-511.
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同型半胱氨酸、C反应蛋白与血脂相关指标对冠心病诊断的比较()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年06期
页码:
509-511
栏目:
出版日期:
2011-11-20

文章信息/Info

Title:
Evaluation of serum homocysteine,C-reactive protein and various lipid lipoprotein in diagnosis of coronary heart disease
文章编号:
1672-271X(2011)06-0509-03
作者:
林 杰; 陈力平; 肖 立; 袁俊菲
214044 江苏无锡,解放军101医院检验科
Author(s):
LIN Jie; CHEN Li-ping; XIAO Li; YUAN Jun-fei
Department of Laboratory,101 Hospital of PLA,Wuxi,Jiangsu 214044,China
关键词:
冠心病; 同型半胱氨酸; C反应蛋白; 脂蛋白(a); 血脂
Keywords:
coronary heart disease;  homocysteine;  C-reactive protein;  lipoprotein(a);  serum lipid
分类号:
R541.4
DOI:
-
文献标志码:
A
摘要:
目的 探讨血清同型半胱氨酸(Hcy)、C反应蛋白(CRP)、脂蛋白(a)[LP(a)]、总胆固醇(T-Cho)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及其有关比值对冠心病的诊断价值，并进行对比与评价。方法 测定135例冠心病患者的Hcy、CRP、LP(a)、T-Cho、HDL-C、LDL-C水平并计算T-Cho/HDL-C比值，与非冠心病对照组112例进行比较，对比各指标对冠心病的诊断价值。结果 冠心病组Hcy、CRP、LP(a)、T-Cho、LDL-C浓度与T-Cho/HDL-C比值明显高于对照组(P<0.05)，HDL-C浓度明显低于对照组(P<0.05)，联合检测Hcy、LP(a)、T-Cho/HDL-C约登指数最大(达到76%)。结论 Hcy与血脂指标联合检测时，可进一步提高其对冠心病的预测和诊断价值。
Abstract:
Objective To evaluate the diagnostic value of serum homocysteine (Hcy),C-reactive protein(CRP),lipoprotein(a),total cholesterol (T-Cho),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol (LDL-C) and T-Cho/LDL-C in coronary heart disease (CHD). Methods Hcy,CRP,LP(a),T-Cho HDL-C and LDL-C were measured in 135 patients with coronary heart disease (CHD) and in 112 controls. The ratio of T-Cho to LDL-C were calculated and the results were evaluated.Results Compared with control group,the levels of Hcy,CRP,LP(a),T-Cho,LDL-C and the ratio of T-Cho to LDL-C in CHD group were significantly raised (P<0.05),whereas the level of LDL-C were significantly decreased (P<0.05). When combined detection of Hcy,LP (a),T-Cho/HDL-C,the Youdens index reached a maximum of 76%.Conclusion The Hcy,LP(a) and T-Cho/LDL-C have diagnostic value for CHD,and should better for diagnosis if combined with their combination.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2011-11-20