|本期目录/Table of Contents|

[1]宋金钧,熊基玲,曹之清,等.滑膜脂肪瘤病的临床病理诊断[J].医学研究与战创伤救治(原医学研究生学报),2014,16(02):153-156.[doi:10.3969/j.issn.1672-271X.2014.02.013]
　SONG Jin-jun,XIONG Ji-ling,CAO Zhi-qing,et al.Synovial lipomatosis:two cases report and review of literature[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2014,16(02):153-156.[doi:10.3969/j.issn.1672-271X.2014.02.013]
点击复制

滑膜脂肪瘤病的临床病理诊断()
分享到62.8K

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第16卷
期数:
2014年02期
页码:
153-156
栏目:
出版日期:
2014-03-20

文章信息/Info

Title:
Synovial lipomatosis:two cases report and review of literature
作者:
宋金钧; 熊基玲; 曹之清; 雷心莉
332000 江西九江，南京军区庐山疗养院病理科
Author(s):
SONG Jin-jun; XIONG Ji-ling; CAO Zhi-qing; LEI Xin-li.
Department of Pathology,Lushan Sanatorium of Nanjing Military Command,Jiujiang,Jiangxi 332000,China
关键词:
滑膜脂肪瘤病; 临床; 病理; 鉴别诊断
Keywords:
synovial lipomatosis; clinical; pathology; differential diagnosis
分类号:
R738.5
DOI:
10.3969/j.issn.1672-271X.2014.02.013
文献标志码:
A
摘要:
目的 探讨滑膜脂肪瘤病的临床病理学特征与鉴别诊断。方法 报道2例关节滑膜脂肪瘤病，对其进行临床病理学分析并文献复习。结果 1例发生在膝关节，1例发生在髋关 节，主要临床症状都是关节疼痛和肿胀，实验室检查无明显异常，其中1例MRI显示关节腔积液，滑膜呈棕榈叶状增生、肥厚。组织学检查显示2例滑膜组织呈绒毛状增生，部分绒毛 被覆的滑膜细胞有不同程度增生，绒毛上皮下可见灶性或弥漫的成熟脂肪细胞浸润，少至中量的淋巴细胞、浆细胞及扩张充血的毛细血管在两例都能看到。结论 滑膜脂肪瘤病是一 种罕见的病因不明的良性关节内病变，对于临床上出现关节疼痛，缓慢发展的关节肿胀以及持续的关节积液的病例，要想到该病的可能，尤其是膝关节，确诊依赖病理组织学诊断 。
Abstract:
Objective To investigate the clinicopathologic features and differential diagnosis of synovial lipomatosis.Methods Two cases of synovial lipomatosis were reported,and the related literatures were reviewed as well.Results Two cases of synovial lipomatosis were diagnosed on histopathology from year 2010 to 2013,with one in the knee joint and another in the hip joint.Pain and swelling of the joint were major complaints.No abnormality was detected in any laboratory tests.MRI showed joint effusion and the synovium suprapatellar bursas remarkably thickened,like palm leaves in a case.On histopathological examination,two cases showed villous proliferation of the synovium with focal and diffuse infiltration by mature adipocytes,amild-to-moderate chronic inflammatory cells infiltrate and congested capillaries were present in two cases.Conclusion Synovial lipomatosis is a rare benign intra-articular lesion of unknown etiology.It should be considered in patients with slowly progressive joint pain and swelling,persistent joint effusion,especially the knee,and histopathology is mandatory for a conclusive diagnosis of synovial lipomatosis.

参考文献/References:

[1] 杨 宇．左膝髌韧带损伤致髌骨半脱位并滑膜脂肪瘤一例[J]．陕西中医学院学报，2000,23(2):25．
[2] 李书宇，崔建国．滑膜脂肪瘤病影像诊断 [J]．中华临床医学卫生杂志，2005,3(11):97．
[3] 杜媚娟，袁传涛，刘爱军．右膝关节内滑膜脂肪瘤１例[J]．诊断病理学杂志，2010,17(1):76．
[4] 高振华，孟俊非，刘大伟．一例膝关节树枝状脂肪瘤的影像表现[J]．中华放射学杂志，2010,44(3):331．
[5] 夏晓丽，郭 荣．膝关节树枝状脂肪瘤一例[J]．中国医药，2012,7(12):1549．
[6] Bejia I,Younes M,Moussa A,et al.Lipoma arborescens affecting multiple joints[J].Skeletal Radiol,2005,34(9):536-538.
[7] Babar SA,Sandison A,Mitchell AW.Synovial and tenosynovial lipoma arborescens of zhe ankle in an adult:a case report[J].Skeletal Radiol,2008,37(1):75-77.
[8] Al-Shraim MM.Intra-articular lipoma arborescens of the knee joint[J].Ann Saudi Med,2011,31(2):194-196.
[9] Ensafdaran A,Vosoughi AR,Khozai A,et al.Lipoma arborescens of the knee:report of a case with full range of motion[J].Middle East J Cancer,2010,1(1):51- 54.
[10] 任富继，赵 力，王瑞琳，等．膝关节滑膜脂肪瘤病的诊断与治疗[J]．中华骨科杂志，2009，29(6):539-543．
[11] Shalinee R,Aarthi R,Mintu JE,et al.Pathology of synovial lipomatosis and its clinical significance[J].J Lab Physicions,2011,3(2):84-88.
[12] Hallel T,Lew S,Bansal M,et al.Villous lipomatous proliferation of the synovial membrance(lipoma arborescens)[J].J Bone Joint Surg Am,1988,70(2):264-270.
[13] 范钦和，朱雄增，赖日权．软组织病理学[M]．南昌:江西科学技术出版社，2003:219．
[14] 武忠弼,杨光华．中华外科病理学:下卷[Ｍ]．北京:人民卫生出版社，2002:2339．
[15] 刘年元,陈友兰,何小鹏,等．膝关节树枝状脂肪瘤的MRI诊断[J]．实用放射杂志，2012,28(8):1248-1250．
[16] Marui T,Yamamoto T,Kimura T,et al.A true intra-articular lipoma of the knee in a girl[J].Arthroscopy,2002,18(5):E24.

相似文献/References:

[1]时维东,陶小红,丁汇清,等.女性肺癌的影像诊断与临床对照分析[J].医学研究与战创伤救治(原医学研究生学报),2013,15(01):35.
　SHI Wei-dong,TAO Xiao-hong,DING Hui-qing,et al.Imaging diagnosis and clinical comparative study of lung cancer in female[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2013,15(02):35.
[2]蔡石龙,马芬芬,陈烨,等.声触诊组织成像鉴别临床不易触诊乳腺小结节的应用价值[J].医学研究与战创伤救治(原医学研究生学报),2017,19(02):167.[doi:10.3969/j.issn.1672-271X.2017.02.014]
　CAI Shi-long,MA Fen-fen,CHEN Ye,et al.The application value of virtual touch tissue imaging in differential diagnosis of clinical cannot palpation to small breast nodules[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2017,19(02):167.[doi:10.3969/j.issn.1672-271X.2017.02.014]
[3]王心,陈铖.伴高尿酸血症的原发性IgA肾病的临床及病理特征分析[J].医学研究与战创伤救治(原医学研究生学报),2017,19(06):600.[doi:10.3969/j.issn.1672-271X.2017.06.010]
　WANG Xin,CHEN Cheng.The clinical and pathological features of primary IgA nephropathy with hyperuricemia[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2017,19(02):600.[doi:10.3969/j.issn.1672-271X.2017.06.010]
[4]陈美惠,贾佳,曹燕丽,等.抑郁症患者性激素异常及治疗的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2021,23(6):633.[doi:10.3969/j.issn.1672-271X.2021.06.016]
　CHEN Mei-hui,JIA Jia,CAO Yan-li,et al.Development on hormone abnormalities and treatment in patients with major depression[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(02):633.[doi:10.3969/j.issn.1672-271X.2021.06.016]

备注/Memo

备注/Memo:
-
更新日期/Last Update: 2014-03-20