|本期目录/Table of Contents|

[1]李奕鑫,陈育霞,李勇飞,等.茵柴降脂汤治疗非酒精性脂肪性肝病临床疗效观察[J].医学研究与战创伤救治(原医学研究生学报),2014,16(03):273-274,294.[doi:10.3969/j.issn.1672-271X.2014.03.015]
 LI Yi-xin,CHEN Yu-xia,LI Yong-fei,et al.The clinical observation about Yin Chai Jiang Zhi Tang decoction on patients with nonalcoholic fatty liver disease[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2014,16(03):273-274,294.[doi:10.3969/j.issn.1672-271X.2014.03.015]
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茵柴降脂汤治疗非酒精性脂肪性肝病临床疗效观察()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第16卷
期数:
2014年03期
页码:
273-274,294
栏目:
出版日期:
2014-05-20

文章信息/Info

Title:
The clinical observation about Yin Chai Jiang Zhi Tang decoction on patients with nonalcoholic fatty liver disease
作者:
李奕鑫陈育霞李勇飞庄学山
362000 福建泉州,解放军180医院南京军区临床肝病研究中心
Author(s):
LI Yi-xinCHEN Yu-xiaLI Yong-feiZHUANG Xue-shan.
Live Center of Nanjing Military Command,180 Hospital of PLA,Quanzhou,Fujian 362000,China
关键词:
非酒精性脂肪性肝病中医药三酰甘油体质量指数
Keywords:
NAFLD Chinese medicine triglycerides BMI
分类号:
R259
DOI:
10.3969/j.issn.1672-271X.2014.03.015
文献标志码:
A
摘要:
目的 茵柴降脂汤对非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)患者的临床疗效观察。方法 全部92例符合诊断标准的患者被随机分为治疗组和对照组,治疗组采用茵柴降脂汤治疗,对照组采用口服多烯磷脂酰胆碱胶囊治疗;以1个月为1个疗程,3个疗程结束后进行疗效统计分析。结果 治疗后,两组患者的丙氨酸转氨酶(ALT)、三酰甘油(TG)指标、肝/脾CT值都有显著改善,且各组前后结果对比差异均有统计学意义(P<0.05)。治疗后两组差异无统计学意义(P>0.05),但治疗组的体质量指数(BMI)值改善优于对照组,治疗前后比较,差异有统计学意义(P<0.05)。结论 茵柴降脂汤在降低NAFLD患者血清中ALT、TG指标,提高患者肝/脾CT值方面与常规药物多烯磷脂酰胆碱胶囊效果相当,在降低BMI值方面效果优于多烯磷脂酰胆碱胶囊。
Abstract:
Objective The clinical observation about Yin Chai Jiang Zhi Tang decoction on patients with nonalcoholic fatty liver disease.Methods All 92 patients were randomly divided into treatment group and control group,the treatment group received Yin Chai Jiang Zhi Tang treatment.The control group received oral polyene phosphatidylcholine capsule treatment.And ask the patient to control their weight during treatment,increase physical activity,proper diet.In a month of a course of treatment,the efficacy of the statistical analysis conducted after three courses.Results After treatment,both groups of patients with ALT,TG index,liver/spleen CT values were significantly improved,and the differences were statistically significant results were compared (P<0.05) before and after each group.After treatment,the two groups showed no significant difference (P>0.05),but BMI values to improve the treatment group than the control group,there was significant difference before and after comparison (P<0.05).Conclusion Yin Chai Jiang Zhi Tang can reduce ALT,TG in serum,and improve liver/spleen CT values respects with conventional drugs polyene phosphatidylcholine capsule quite effective in terms of reducing the effect of BMI values than conventional drugs polyene phosphatidyl choline capsules.

参考文献/References:

[1]中华医学会肝脏病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊疗指南[J].中华肝脏病杂志,2010,18(3):161-163.
[2]Farrell GC.Larter CZ.Nonalcoholic fatty liver disease:from steatosis to cirrhosis[J].Hepatology,2006,43(2 Suppl 1):S99-S112.
[3]Angulo P.GI epidemiology:nonalcoholic fatty liver disease[J].Aliment Pharmaeol Ther,2007,25:883-889.
[4]中华中医药学会脾胃病分会.非酒精性脂肪性肝病中医诊疗共识意见(2009,深圳)[J].中国中西医结合消化杂志,2010,18(4):276-279.
[5]王雁翔,丁桂芳,陈理书,等.780例非酒精性脂肪肝中医证候流行病学调查[J].中西医结合肝病杂志,2007,17(6):364-365.
[6]康庆伟,阎 姝.茵陈蒿汤的药理作用及临床应用进展[J].中国中西医结合外科杂志,2013,19(4):473-475.
[7]李 丹,江 涛,范华倩,等.柴胡疏肝散对非酒精性脂肪肝大鼠脂质代谢及肝功能的影响[J].中药药理与临床,2013,29(3):8-11.
[8]职玉娟,黄水清.黄芪、当归药对及当归补血汤对小鼠巨噬细胞吞噬氧化低密度脂蛋白的作用[J].广州中医药大学学报,2013,30(2):200-202,206,283.
[9]王 颖,钟 勇,史兆荣,等.中青年非酒精性脂肪肝与代谢综合征的关系[J].东南国防医药,2012,14(2):144,175.
[10]中国中西医结合学会消化系统疾病专业委员会.非酒精性脂肪性肝病的中西医结合诊疗共识意见[J].中国中西医结合杂志,2011,31(2):155-158.
[11]Dey PK,Sutradhar SR,Barman TK,et al.Risk factors of non-alcoholic fatty liver disease[J].Mymensingh Med J,2013,22(4):649-654.
[12] Miyake T,Kumagi T,Furukawa S,et al.Non-alcoholic fatty liver disease:factors associated with its presence and onset[J].J Gastroenterol Hepatol,2013,28(4):71-78.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2014-05-20