|本期目录/Table of Contents|

[1]王妍亭,韩娟,刘进衡综述,等.上皮膜蛋白1的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2018,20(01):50-53.[doi:10.3969/j.issn.1672-271X.2018.01.011]
点击复制

上皮膜蛋白1的研究进展()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年01期
页码:
50-53
栏目:
综述
出版日期:
2018-01-22

文章信息/Info

Title:
-
作者:
王妍亭韩娟刘进衡综述颜浩审校
作者单位:610017成都,成都市第二人医院呼吸内科(王妍亭、韩娟、颜浩),肝胆外科(刘进衡)
Author(s):
-
关键词:
上皮膜蛋白1外周髓鞘蛋白-22肿瘤
Keywords:
-
分类号:
R739
DOI:
10.3969/j.issn.1672-271X.2018.01.011
文献标志码:
A
摘要:
上皮膜蛋白1(EMP1)属跨膜蛋白家族亚组,分布于人体多种组织,在细胞的生长、增殖、分化、凋亡中具有重要的调节功能。并与肿瘤的发生、进展相关。EMP1可望成为新的生物学标记,为肿瘤的筛查、判断病情严重程度以及指导治疗提供一条可行的途径。
Abstract:
-

参考文献/References:

[1]Taylor V, Welcher AA, Program AE,et al. Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family[J]. J Biol Chem, 1995, 270(48):28824-28833.[2]张海涛, 卢亦成. 上皮膜蛋白1基因及相关分子在脑胶质瘤中的研究进展[J]. 中华神经医学杂志, 2010, 9(8):859-861.[3]Ben-Porath I, Kozak CA, Benvenisty N. Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encodingmembrane proteins related to Pmp22[J]. Genomics, 1998, 49(3):443-447.[4]Jetten AM, Suter U. The peripheral myelin protein 22 and epithelial membrane protein family[J]. Prog Nucleic Acid Res Mol Biol, 2000,64:97-129.[5]Ahmad KA, Wang G, Unger G, et al. Protein kinase CK2--a key suppressor of apoptosis[J]. Adv Enzyme Regul, 2008, 48:179-187.[6]Shrivastav A, Sharma AR, Bajaj G, et al. Elevated N-myristoyltransferase activity and expression in oral squamous cell carcinoma[J]. Oncol Rep, 2007, 18(1):93-97.[7]Marvin KW, Fujimoto W, Jetten AM. Identification and characterization of a novel squamous cell-associated gene related to PMP22[J]. J Biol Chem, 1995, 270(48):28910-28916.[8]Li ZY, Xiong SH, Hu M, et al. Epithelial membrane protein 1 inhibits human spinal chondrocyte differentiation[J]. Anat Rec (Hoboken), 2011, 294(6):1015-1024.[9]Chen Y, Medvedev A, Ruzanov P, et al. cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family[J]. Genomics, 1997, 41(1):40-48.[10]Ruegg CL, Wu HY, Fagnoni FF, et al. B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain[J]. J Immunol, 1996, 157(1):72-80.[11]Wang HT, Kong JP, Ding F, et al. Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNAMicroarray[J]. World J Gastroenterol, 2003, 9(3):392-398.[12]Ben-Porath I, Benvenisty N. Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins[J]. Gene, 1996, 183(1-2):69-75.[13]Sun GG, Wang YD, Lu YF, et al. EMP1, a member of a new family of antiproliferative genes in breast carcinoma[J]. Tumour Biol, 2014, 35(4):3347-3354.[14]Sun GG, Wang YD, Cui DW, et al. Epithelial membrane protein 1 negatively regulates cell growth and metastasis in colorectal carcinoma[J]. World J Gastroenterol, 2014, 20(14):4001-4010.[15]Sun GG, Lu YF, Fu ZZ, et al. EMP1 inhibits nasopharyngeal cancer cell growth and metastasis through induction apoptosis and angiogenesis[J]. Tumour Biol, 2014, 35(4):3185-3193.[16]Sun GG, Wang YD, Cui DW, et al. EMP1 regulates caspase-9 and VEGFC expression and suppresses prostate cancer cellproliferation and invasion[J]. Tumour Biol, 2014, 35(4):3455-3462.[17]Demirag GG, Kefeli M, Kemal Y, et al. Epithelial membrane protein 1 expression in ovarian serous tumors[J]. Oncol Lett, 2016, 11(3):2140-2144.[18]丁振, 崔巍, 韩磊,等. SNAT1和EMP1在胃癌组织和细胞株中的表达及临床意义[J]. 临床肿瘤学杂志, 2014, (9):809-813.[19]孙国贵, 付占昭, 杨从容,等. 鼻咽癌中EMP1蛋白的表达及其临床意义[J]. 癌变 畸变 突变, 2014, 26(4):301-304.[20]代晓华, 张军, 连小丽,等. 上皮膜蛋白1真核表达载体的构建及其对人舌鳞状细胞癌细胞迁移和侵袭的影响[J]. 华西口腔医学杂志, 2016, 34(4):398-403.[21]Lai S, Wang G, Cao X, et al. EMP-1 promotes tumorigenesis of NSCLC through PI3K/AKT pathway[J]. J Huazhong Univ Sci Technolog Med Sci, 2012, 32(6):834-838.[22]张海涛, 卢亦成, 何金. EMP1基因在人脑胶质瘤中的表达及其临床意义[J]. 中国肿瘤生物治疗杂志, 2007, 14(5):466-470.[23]Jain A, Tindell CA, Laux I, et al. Epithelial membrane protein-1 is a biomarker of gefitinib resistance[J]. Proc Natl Acad Sci USA, 2005, 102(33):11858-11863.[24]Ramnarain DB, Park S, Lee DY, et al. Differential gene expression analysis reveals generation of an autocrine loop by a mutantepidermal growth factor receptor in glioma cells[J]. Cancer Res, 2006, 66(2):867-874.[25]Durgan J, Tao G, Walters MS, et al. SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1[J]. EMBO Rep, 2015, 16(1):87-96.[26]Aris IM, Jerchel IS, van den Dungen RE, et al. EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion[J]. Leukemia, 2014, 28(9):1828-1837.[27]程伟, 李幼生. 精准医学理念在临床实践中的运用进展[J]. 医学研究生学报, 2016, 29(4): 440-444.

相似文献/References:

备注/Memo

备注/Memo:
基金项目:成都市科技惠民项目(2015-HM01-00099-SF)
更新日期/Last Update: 2018-01-20