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[1]王鹏,江海洋,赵超,等.不同标本类型C反应蛋白检测结果的一致性分析[J].医学研究与战创伤救治(原医学研究生学报),2019,21(3):254-257.[doi:10.3969/j.issn.1672-271X.2019.03.007]
 WANG Peng,JIANG Hai-yang,ZHAO Chao,et al.Consistency analysis of CRP results in different types of samples[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2019,21(3):254-257.[doi:10.3969/j.issn.1672-271X.2019.03.007]
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不同标本类型C反应蛋白检测结果的一致性分析()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第21卷
期数:
2019年3期
页码:
254-257
栏目:
出版日期:
2019-05-10

文章信息/Info

Title:
Consistency analysis of CRP results in different types of samples
文章编号:
1672-271X(2019)03-0254-04
作者:
王鹏 江海洋 赵超 徐广峰 陈诚 谢晖
作者单位:223001淮安,东部战区总医院(原八二医院)检验科(王 鹏、江海洋、赵 超、徐广峰、陈 诚、谢 晖)
Author(s):
WANG Peng JIANG Hai-yang ZHAO Chao XU Guang-feng CHEN Cheng XIE Hui
(Department of Clinical Laboratory,General Hospital of Eastern Theater Command,PLA,Huaian 223001,Jiangsu,China)
关键词:
C反应蛋白 全血 血浆 血清 对比分析
Keywords:
C-reactive protein(CRP) whole blood plasma serum comparative analysis
分类号:
R446.1
DOI:
10.3969/j.issn.1672-271X.2019.03.007
文献标志码:
A
摘要:
目的 探讨PENTRA MS CRP分析仪检测全血标本与TBA2000FR全自动生化分析仪检测血浆、血清标本C反应蛋白(CRP)结果的可比性及相关性。 方法 随机留取2017年5-7月东部战区总医院(原八二医院)93例门诊及住院患者EDTA-K2抗凝血与非抗凝血标本(57例抗凝标本,36例血清标本),分别采用PENTRA MS CRP分析仪检测全血标本CRP浓度,TBA2000FR全自动生化分析仪检测血浆与血清CRP浓度。根据全血CRP浓度,将受试者分为低值组(<5 μg/mL)、中值组(5~20 μg/mL)和高值组(>20 μg/mL),分别对全血CRP浓度与血浆、血清CRP浓度进行比对分析。 结果 在低值组、中值组及高值组中,全血CRP与血浆CRP之间(r值分别为0.941、0.974、0.964),全血CRP与血清CRP之间(r值分别为0.995、0.966、0.996)均呈良好的相关性,差异均有统计学意义( P<0.05),其中全血CRP与血清CRP之间差异在临床可接受范围内。 结论 血浆标本不适于直接在TBA2000FR全自动生化分析仪检测,全血标本与血清标本分别在2个检测系统的检验结果具有一致性。
Abstract:
Objective To investigate the comparability and correlation of whole blood,plasma and serum C-reactive protein (CRP) in PENTRA MS CRP analyzer and TBA2000FR automatic biochemical analyzer. Methods 93 EDTA-K2 anticoagulant and non-anticoagulant specimens from outpatients and inpatients in our hospital were randomly collected(57 anticoagulant specimens, 36 serum specimens).The CRP concentration of whole blood specimen was detected by PENTRA MS CRP analyzer,The CRP concentration of plasma and serum specimens was detected by TBA2000FR automatic biochemical analyzer. The subjects divided into the low value (<5 μg/mL),median value(5-20 μg/mL) and high value (>20 μg/mL) group according to the CRP concentration of whole blood. The whole blood,plasma and serum CRP concentration was compared and analyzed. Results There was a good correlation between plasma CRP and whole blood CRP (R values were 0.941,0.974,0.964 respectively) and between serum CRP and whole blood CRP (R values were 0.995,0.966,0.996 respectively) in low value group,middle value group and high value group,and there were significant differences (P<0.05). The bias of the whole blood CRP and serum CRP is within the clinical acceptable range. Conclusion Plasma samples are not suitable for direct detection by TBA2000FR automatic biochemical analyzer. The results of whole blood samples and serum samples are consistent in the two detecting systems.

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备注/Memo

备注/Memo:
收稿日期:2018-09-05
更新日期/Last Update: 2019-05-10