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[1]李福兴,张自华,李雪梅,等.中性粒细胞胞外诱捕网在炎症性疾病中的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2021,23(04):378-382.[doi:10.3969/j.issn.1672-271X.2021.04.009]
　LI Fu-xing,ZHANG Zi-hua,LI Xue-mei,et al.Advances in research on the neutrophil extracellular traps in inflammatory diseases[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(04):378-382.[doi:10.3969/j.issn.1672-271X.2021.04.009]
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中性粒细胞胞外诱捕网在炎症性疾病中的研究进展()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年04期
页码:
378-382
栏目:
综述
出版日期:
2021-08-10

文章信息/Info

Title:
Advances in research on the neutrophil extracellular traps in inflammatory diseases
作者:
李福兴;  张自华;  李雪梅;  赵卫东
作者单位：671000大理，大理大学临床医学院(李福兴、赵卫东)；671000大理，大理大学第一附属医院检验科(张自华、李雪梅)
Author(s):
LI Fu-xing1;  ZHANG Zi-hua2;  LI Xue-mei2 ;  ZHAO Wei-dong1
（1.Clinical Medical College, Dali University, Dali 671000, Yunnan, China；2.Department of Laboratory Medicine, The First Affiliated Hospital of Dali University, Dali 671000, Yunnan, China）
关键词:
中性粒细胞; 中性粒细胞胞外诱捕网; 炎症性疾病
Keywords:
neutrophil;  neutrophil extracellular traps;  inflammatory diseases
分类号:
R392.11
DOI:
10.3969/j.issn.1672-271X.2021.04.009
文献标志码:
A
摘要:
中性粒细胞胞外诱捕网（NETs）的形成过程称为NETosis，是不同于凋亡和坏死的一种新型中性粒细胞死亡方式，其机制包括经典途径及Gasdermin D介导的途径。NETs在炎症性疾病（ID）的发生发展中发挥重要作用。文章就NETs在肿瘤、自身免疫性疾病、心脑血管疾病、糖尿病及感染性疾病等ID中作用的研究进展进行综述。
Abstract:
The state of neutrophil with Neutrophil Extracellular Traps (NETs) formation is termed NETosis, a new type of cell death, which is different from apoptosis and necrosis. Mechanisms of NETosis include classical pathway and Gasdermin D mediated pathway. Some studies have proved that NETs might play important roles in inflammatory diseases (ID). Herein, we review recent advances in the knowledge of NETs in tumor, autoimmune disease, cardiovascular and cerebrovascular disease, diabetes and infectious diseases, and provide fresh ideas for the treatment of ID.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金(81960363)；云南省教育厅科学研究基金研究生项目(2021Y429)
更新日期/Last Update: 2021-08-10