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[1]冯念,徐捷,唐胜滢,等.实时超声造影与增强螺旋CT对直径<3 cm肝占位病变的诊断价值比较[J].医学研究与战创伤救治(原医学研究生学报),2021,23(05):501-505.[doi:10.3969/j.issn.1672-271X.2021.05.012]
　FENG Nian,XU Jie,TANG Sheng-ying,et al.Comparisonon the clinical value of real-time contrast-enhanced ultrasonography and contrast-enhanced CT in diagnosis of focal liver lesions less than 3 cm[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(05):501-505.[doi:10.3969/j.issn.1672-271X.2021.05.012]
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实时超声造影与增强螺旋CT对直径<3 cm肝占位病变的诊断价值比较()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年05
页码:
501-505
栏目:
临床研究
出版日期:
2021-09-20

文章信息/Info

Title:
Comparisonon the clinical value of real-time contrast-enhanced ultrasonography and contrast-enhanced CT in diagnosis of focal liver lesions less than 3 cm
作者:
冯念; 徐捷; 唐胜滢; 黄艳丽
作者单位：210002南京，东部战区总医院秦淮医疗区特诊科（冯念、徐捷、唐胜滢、黄艳丽）
Author(s):
FENG Nian;  XU Jie;  TANG Sheng-ying; HUANG Yan-li
(Department of Special Diagnosis, Qinhuai Medical Treatment Area of General Hospital of Eastern Theater Command，PLA，Nanjing 210002，Jiangsu，China）
关键词:
实时超声造影; 增强螺旋CT; 肝占位病变
Keywords:
real-time contrast-enhanced ultrasonography;  contrast-enhanced CT; focal liver lesions
分类号:
R445.1
DOI:
10.3969/j.issn.1672-271X.2021.05.012
文献标志码:
A
摘要:
目的比较实时超声造影与增强螺旋CT在诊断直径＜3cm的肝占位性病变中的诊断价值。方法回顾性分析东部战区总医院秦淮医疗区2017年1月到2020年1月290例肝占位性病变患者的影像资料，观察比较同一病灶在超声造影和增强螺旋CT检查下的诊断结果，并与手术病理结果比较，分析超声造影和增强螺旋CT诊断的特异性、灵敏性和准确性。结果对于直径＜3 cm的肝占位病变，实时超声造影的特异性98.64%、灵敏性97.20%、准确性97.93%，增强螺旋CT检查的特异性92.52%、灵敏性88.81%、准确性90.69%，差异均有统计学意义（P＜0.05）。实时超声造影ROC曲线下面积（AUC）为 0.978，标准误为 0.045，增强螺旋CT的ROC曲线下面积（AUC）为 0.813，标准误为 0.067，差异有统计学意义（P＜0.05）。实时超声造影检查肝恶性占位病变的平均通过时间、上升时间、达峰时间明显少于良性病变（P＜0.01），灌注指数明显大于良性病变（P＜0.01）。结论在直径＜3 cm肝占位病变的诊断中，实时超声造影的特异性、灵敏性、准确性比增强螺旋CT更高，具有临床应用价值。
Abstract:
ObjectiveTo compare the clinical value of real-time contrast-enhanced ultrasound and enhanced spiral CT in diagnosis focal liver lesions less than 3 cm.MethodsA total of 290 patients with focal liver lesions less than 3 cm were enrolled in this study from January 2017 to January 2020. The diagnosis results of the contrast-enhanced ultrasound and enhanced spiral CT were observed and compared retrospectively. The accuracy, sensitivity and specificity of contrast-enhanced ultrasonography and enhanced spiral CT were analyzed compared with the results of surgery and pathology.ResultsFor the focal liver lesions less than 3 cm, the specificity, sensitivity, and accuracy of real-time contrast-enhanced ultrasound was 98.64%, 97.20%, and 97.93%, respectively. The specificity, sensitivity, and accuracy of enhanced spiral CT was 92.52%, 88.81%, and 90.69%, respectively. There were significant differences between the two groups (P<0.05). The area under the ROC curve of real-time contrast-enhanced ultrasound was 0.978 and the standard error was 0.045. The area under the ROC curve of enhanced spiral CT was 0.813 and the standard error was 0.067 (P<0.05). In real-time contrast-enhanced ultrasound examination, the average transit time, rise time, and peak time of malignant focal liver lesions were less than benign lesions (P<0.05), and the perfusion index was greater than benign (P<0.05).ConclusionFor the focal liver lesions less than 3 cm, real-time contrast-enhanced ultrasound has higher specificity, sensitivity and accuracy than enhanced spiral CT, which has clinical value.

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更新日期/Last Update: 2021-10-11