[1]晏雪婷,程苏琴,朱美财,等.高空电磁辐射对运输机飞行员免疫球蛋白与补体的影响[J].医学研究与战创伤救治(原医学研究生学报),2015,17(04):339-341.[doi:10.3969/j.issn.1672-271X.2015.04.001]
YAN Xue-ting,CHENG Su-qin,ZHU Mei-cai,et al.Effects of electromagnetic radiation on the immunoglobulin and complement of transport pilots[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2015,17(04):339-341.[doi:10.3969/j.issn.1672-271X.2015.04.001]
点击复制
高空电磁辐射对运输机飞行员免疫球蛋白与补体的影响()
《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]
- 卷:
-
第17卷
- 期数:
-
2015年04期
- 页码:
-
339-341
- 栏目:
-
- 出版日期:
-
2015-07-20
文章信息/Info
- Title:
-
Effects of electromagnetic radiation on the immunoglobulin and complement of transport pilots
- 作者:
-
晏雪婷; 程苏琴; 朱美财; 孙绍权
-
100142 北京,空军总医院临床检验中心
- Author(s):
-
YAN Xue-ting; CHENG Su-qin; ZHU Mei-cai; SUN Shao-quan.
-
Clinical Laboratory Center, Air Force General Hospital, Beijing 100142, China
-
- 关键词:
-
电磁辐射; 运输机; 飞行员; 补体; 免疫球蛋白
- Keywords:
-
electromagnetic radiation; transport; pilots; complement; immunoglobulin
- 分类号:
-
R446.62;R594.8
- DOI:
-
10.3969/j.issn.1672-271X.2015.04.001
- 文献标志码:
-
A
- 摘要:
-
目的 研究飞行环境中高空电磁辐射对运输机飞行员外周血免疫球蛋白(IgG、IgA、 IgM)和补体(C3、C4)水平的影响,以及飞行时间与各指标的相关性。方法 检测120名运输机飞行员(观察组)和100名地勤工作人员(对照组)外周血免疫球蛋白和补体水平。按飞行时间将运输机飞行员分为4组,分别与对照组进行比较,并分析飞行时间与各指标的相关性。结果 与对照组相比,运输机飞行员的IgG、IgM水平降低,C3、C4水平增高(P<0.05),IgA的差异无统计学意义(P>0.05)。飞行<1000 h组的C3、C4水平增高;1000~1999 h组的IgG水平降低,C3、C4增高;2000~3000 h组的IgG水平降低;>3000 h组的IgM水平降低,C3、C4增高(P<0.05)。飞行时间与IgM水平之间存在一定的相关性(r为-0.154,P<0.05),模拟出幂函数模型Y=1.904(X-0.094),与其他指标之间无相关性。结论 高空飞行环境下,运输机飞行员的免疫指标会发生改变,IgG、IgM降低,C3、C4增高,并且IgM随着飞行时间的增加而降低。
- Abstract:
-
Objective To study the effects of electromagnetic radiation in flying environment on the immunity indexes(IgG, IgA, IgM, C3 and C4) of transport pilots in peripheral blood and correlation analysis of flight time with each index. Methods The immunoglobulin and complement of 120 transport pilots and 100 ground workers were detected. According to the flying time, transport pilots were divided into 4 groups, respectively:flying below 1000 h group, 1000-1999 h group, 2000-3000 h group and group above 3000 h. For all above ground, the ground staffs were used as control. The correlation between flight time and each index were analysed. Results Compared with the control group, IgG and IgM of the transport pilots decreased, C3 and C4 increased (P<0.05). There was no statistically significant different of IgA (P>0.05). C3 and C4 of the transport pilots who flying below 1000 h increased;as for the group of 1000-1999 h, IgG decreased, C3 and C4 increased; IgG of the 2000-3000 h group decreased; IgM of the group exceed 3000 h decreased, C3 and C4 increased (P<0.05). There was a certain correlation between the time of flight and IgM (r=-0.154, P<0.05), simulate the power model of Y=1.904 (X-0.094), but there were no correlations with other indicators. Conclusion The immune indexes of transport pilots will change in the flying environment, IgG and IgM of the transport pilots decreased, C3, C4 increased and IgM decreased with the increase of time of flight.
参考文献/References:
[1]任兆生,李路平,李俊勤,等.高温、噪声、振动复合应激时人体血压和缩血管激素的变化[J].中华航空航天医学杂志,1997,8(2):111-114.
[2]De Luca C1,Deeva I,Mariani S.et al.Monitoring antioxidant defenses and free radical production in space-flight,aviation and railway engine operators,for the prevention and treatment of oxidative stress,immunological impairment,and pre-mature cell aging[J].Toxicol Ind Health,2009,25(4-5):259-267.
[3]沈思云,白 菁.浅谈飞行员缺氧训练中的护理体会[J].东南国防医药,2007,9(4):298-299.
[4]冯英进,陈蔚如,仲 晶.飞行人员宇宙辐射有效剂量的估算和分析[J].环境与职业医学,2004,21(4):271-274.
[5]于繁荣.巨细胞病毒感染与宿主的免疫机能损伤[J].南京部队医药,1998,1(2):78-80.
[6]宋水江,张成国,黄鉴政.脑血管病患者体液免疫功能的初步研究[J].浙江大学学报:医学版,1995,24(4):148-150.
[7]刘继文,王治明,王绵珍,等.职业紧张对免疫功能的影响[J].中国工业医学杂志,2002,15(2):100-101.
[8]张育红,李国玉,孙 磊,等.医务人员职业紧张与补体水平关系研究[J].中国工业医学杂志,2010,23(4):289-291.
[9]李卫东,薛 霞,薛 红,等.高+Gz暴露对飞行员唾液分泌型免疫球蛋白A和皮质醇浓度的影响[J].中华航空航天医学杂志,2013,24(2):113-116.
[10]拓 飞,姚永祥,周 炼,等.极地与非极地航线空勤人员所受光子和中子宇宙辐射剂量比较[J].中华放射医学与防护杂志,2010,30(4):469-471.
[11]李延忠,陈少华,赵科伕,等.微波辐射对机体健康和免疫功能的影响[J].中华劳动卫生职业病杂志,2013,31(8):602-605.
[12]刘新梅,谭卫国,曾 红,等.某市放射作业人员免疫球蛋白含量的影响分析[J].工业卫生与职业病,2012,38(1):47-48.
[13]彭章平,白 菁,冯松锦,等.飞行员外周血T淋巴细胞免疫功能初步研究[J].环境与健康杂志,1999,16(4):210-212.
[14]郭 瑛,崔玉芳,李 燕,等.高功率微波对大鼠免疫组织活性氧水平的影响[J].中国预防医学杂志,2007,8(5):528-530.
[15]徐 莉,周林甫,扬长斌,等.临潼疗养地自然疗养因子对飞行员免疫功能的影响[J].中华保健医学杂志,2010,12(6):465-466.
备注/Memo
- 备注/Memo:
-
总后卫生部2013年部队应用性研究课题(13BJYZ24)
更新日期/Last Update:
2015-07-20