|本期目录/Table of Contents|

[1]沈小玥,穆晓苏,徐晓莉,等.9例大面积烧伤合并吸入性气道损伤患者下呼吸道感染的预防与控制[J].医学研究与战创伤救治(原医学研究生学报),2016,18(02):113-115,130.[doi:10.3969/j.issn.1672-271X.2016.02.001]
 SHEN Xiao-yue,MU Xiao-su,XU Xiao-li,et al.The prevention and control of lower respiratory tract infection in 9 cases of patients with large area burn combined inhalation injury[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(02):113-115,130.[doi:10.3969/j.issn.1672-271X.2016.02.001]
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9例大面积烧伤合并吸入性气道损伤患者下呼吸道感染的预防与控制()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第18卷
期数:
2016年02期
页码:
113-115,130
栏目:
出版日期:
2016-04-09

文章信息/Info

Title:
The prevention and control of lower respiratory tract infection in 9 cases of patients with large area burn combined inhalation injury
作者:
沈小玥穆晓苏徐晓莉黄慧敏方红梅尹湘毅李亚楠尹诺
210002 江苏南京,南京军区南京总医院感染管理科
Author(s):
SHEN Xiao-yue MU Xiao-su XU Xiao-li HANG Hui-min FANG Hong-mei YIN Xiang-yi LI Ya-nan YIN Nuo.
Department of Infectious Management, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing, Jiangsu 210002, China
关键词:
大面积烧伤吸入性气道损伤耐药性下呼吸道感染预防与控制
Keywords:
large area burn inhalation injury drug resistance lower respiratory tract infection infection prevention and control
分类号:
R644
DOI:
10.3969/j.issn.1672-271X.2016.02.001
文献标志码:
A
摘要:
目的 探讨9例大面积烧伤合并吸入性气道损伤患者下呼吸道感染的预防与控制措施。方法 调查9例大面积烧伤合并吸入性损伤患者的下呼吸道分泌物培养的病原菌细菌谱及耐药情况。结果 共检出下呼吸道病原菌2种,共38株,其中鲍曼不动杆菌37株,占97.36%(37/38);嗜麦芽假单胞菌1株,占2.64%(1/38)。鲍曼不动杆菌耐药率达到75.59%,对替加环素、米诺环素敏感性90%以上。经过严格实施感染预防与控制,合理使用抗菌药物等综合措施后取得了良好的疗效,鲍曼不动杆菌检出率明显下降。结论 本文患者的下呼吸道病原菌以鲍曼不动杆菌最常见,虽然鲍曼不动杆菌感染率及耐药率高,但可以通过有效的消毒隔离、严格的下呼吸道医院感染预防措施及合理应用抗菌药物等方法,使鲍曼不动杆菌的检出率明显下降。
Abstract:
Objective To prevent and reduce lower respiratory tract infection in the batch of patients with large area burn combined inhalation injury. Methods 9 cases of large area burn with inhalation injury patients were investigated of bacterial spectrum and drug resistance of lower respiratory tract secretion. Results In the survey, we detected a total of 38 strains of 2 kinds of the lower respiratory tract pathogen, including 37 strains of acinetobacter baumannii accounting for 97.36% and 1 strain of eosinophilic malt pseudomonas accounting for 2.64%. Acinetobacter baumannii antibiotic resistant rate rised up to 75.59%. The sensitive rate of tigecycline and minocycline rised significantly (>90%). After strict infection control, reasonable use of antibiotics and other comprehensive measures, we have obtained a good curative effect. The detection rate of acinetobacter baumannii declined obviously. Conclusion In large area burn with inhalation injury patients, acinetobacter baumannii is the most common in lower respiratory tract pathogen species. Although highly acinetobacter baumannii infection rate and drug resistance of lower respiratory tract secretion in the batch of patients with arge area burn combined inhalation injury, acinetobacter baumannii control can achieve good effect through effective disinfection isolation, strict artificial airway infection prevention and control, reasonable application of antimicrobial agents and other methods.

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备注/Memo

备注/Memo:
中华医院感染控制研究基金(ZHYG2014-0037);全军后勤科研计划课题(CNJ14L004);南京军区医学科技创新课题(14MS106);南京总医院军事医学项目(YYMS2014017);中国博士后科学基金面上项目(2014M552701);江苏省博士后科学基金项目(1302073C)
更新日期/Last Update: 2016-03-20