|本期目录/Table of Contents|

[1]崔莲,马建新,刘丽丽,等.肥胖相关指标与结直肠息肉发病关系的探讨[J].医学研究与战创伤救治(原医学研究生学报),2017,19(04):345-347.[doi:10.3969/j.issn.1672-271X.2017.04.003]
　CUI Lian,MA Jian-xin,LIU Li-li,et al.Study on the relationship between obesity-related indexes and pathogenesis of colorectal polyps[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2017,19(04):345-347.[doi:10.3969/j.issn.1672-271X.2017.04.003]
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肥胖相关指标与结直肠息肉发病关系的探讨()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第19卷
期数:
2017年04期
页码:
345-347
栏目:
出版日期:
2017-08-10

文章信息/Info

Title:
Study on the relationship between obesity-related indexes and pathogenesis of colorectal polyps
作者:
崔莲1; 马建新1; 刘丽丽1; 张蓉1; 王光辉1; 霍文静1; 郝淑芳1; 方玮1; 张金萍2
作者单位：100017北京，解放军第305医院，1.干部病房，2.医务部
Author(s):
CUI Lian1; MA Jian-xin1; LIU Li-li1; ZHANG Rong1; WANG Guang-hui1; HUO Wen-jing1; HAO Shu-fang1; FANG Wei1; ZHANG Jin-ping2
(1.Cadre Ward，2. Administration Office，the 305th Hospital of PLA，Beijing 100017，China)
关键词:
肥胖相关指标; 结直肠息肉; 内脏脂肪面积
Keywords:
Obesity-related indexes;  Colorectal polyps;  Visceral fat area
分类号:
R735.3
DOI:
10.3969/j.issn.1672-271X.2017.04.003
文献标志码:
A
摘要:
目的 分析肥胖相关指标与结直肠息肉检出率之间的关系。方法 回顾性分析2013年4月至2016年12月解放军第305医院干部病房住院的男性无症状体检者中同时完成结肠镜及人体成分分析者166例临床资料，分析体重指数、内脏脂肪面积、体脂肪率等指标对结直肠息肉发病的影响。结果 166例男性体检者，检出结直肠息肉72例（43.4%），腺瘤38例（22.9%）。多因素logistic回归分析显示，内脏型肥胖者发生结直肠息肉的概率较内在脂肪面积正常者更高[OR为3.20，95%CI为1.18～8.69]，差异有统计学意义（P＜0.05）。结论 内脏脂肪面积与结直肠息肉发病的相关提示内脏型肥胖患者更容易患结直肠息肉。
Abstract:
Objective Analysis the relationship between different obesity-related indexes and detection rate of colorectal polyps.Methods There were 166 patients who completed colonoscopy and body composition from the patients with asymptomatic health examination from April 2013 to December 2016 hospitalized in our hospital, and retrospective analysis the influence between their body mass index, visceral fat area, body fat percentage and the incidence of colorectal polyps.Results 166 cases of male health examination, 72 cases of colorectal polyps were detected (43.4%)，and 38 cases adenoma (22.9%). Multivariate logistic regression analysis showed that those with higher odds ratio of colorectal polyps were among visceral fat area exceeded standard (OR:3.20, 95% CI:1.18-8.70).Conclusion The visceral fat area is more relevant to the pathogenesis of colorectal polyps in different obesity-related indexes.

参考文献/References:

[1]Trayhum P，Beattie JH．Physiological role of adipose tissue：white adipose tissue as an endocrine and secretory organ[J]．Proc Nutr Soc，2001，60(3)：329-339.
[2］Lima-Martinez MM，Blandeier C, Iacobellis G.Epicardial sdipose tis-sue:more than a simple fat deposit[J]．Endocrinol Nutr，2013，60(6):320-328.
[3］王彦.内脏脂肪面积和胰岛素抵抗标志物与结、直肠肿瘤相关性的研究[J]. 中国临床医生杂志，2015，43(4):66-69.
[4］Nagai M, Komiya H, Mori Y, et al. Development of a new method for estimating visceral fat area with multi-frequency bioelectrical impedance[J]. Tohoku J Exp Med,2008,214(2):105-112.
[5］中华人民共和国卫生部疾病预防控制司. 中国成人超重和肥胖症预防控制指南[M]. 北京:人民卫生出版社，2006:1-27.
[6］Examination Committee Criteria for‘Obesity Disease’ in Japan，Japan Society for the Study of Obesity．New criteria for ‘obesity disease’ in Japan[J]．Circ J，2002，66(11)：987-992.
[7］张荣欣，薛长勇，郑子欣，等. 成人BMI与体脂含量和脂肪分布的关系[J]. 营养学报，2002，24(2): 144-148.
[8］Zauber AG，Winawer SJ，O′Brien MJ，et al．Colonoscopicpolypectomy and long-term prevention of colorectal-cancer deaths[J]．N Engl J Med，2012，366( 8): 687-696.
[9］张荣，黄丽珊，黄艺蓉，等．高成本下医院制剂成本管理控制策略探讨[J]．东南国防医药，2014,16(4):442-444.
[10]Comsrock SS，Hortos K，Kovan B，et al.Adipokines and obesity are associated with colorectal polyps in asult males:a coross-sectional study[J]．PLoS One,2004,9(1):e85939.
[11］刘雷，张新，王瑞峰，等.结直肠息肉与血脂水平的相关性研究[J]. 现代生物医学进展，2016(25):4979-4983.
[12］Kim BC, Shin A, Hong CW, et al. Association of colorectal adenoma with components of metabolic syndrome[J]. Cancer Causes Control,2012,23(5):727-735.
[13］高炳霞，林香春，刘红，等.年龄、性别及肥胖与大肠腺瘤关系的初步探讨[J]. 实用临床医药杂志，2011,15(17):14-19.
[14］Kang HW, Kim D,Kim HJ,et al.Wisceral obesity and insulin resistance as risk factors for colorectal adenoma:acorss-sectional,case-control study[J]. Am J Gastroenterol,2010,105(1):178-187.
[15］Lieberman DA, Williams JL, Holub JL, et al.Race,ethnicity,and sex affect risk for polyps＞9 mm in average-risk individuals[J]. Gastroenterology,2014,147(2):351-358.
[16］Wang FW, Hsu PI, Chuang HY, et al. Prevalence and risk facrors of asymptomatic colorectal polyps in taiwan[J]. Gastroenterol Res Pract,2014,2014:985205. doi: 10.1155/2014/985205.

相似文献/References:

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　CUI Lian,WANG Zhi-jin,MA Jian-xin,et al.Analysis of 328 cases of colorectal polyp inspection results in asymptomatic persons[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(04):125.[doi:10.3969/j.issn.1672-271X.2016.02.005]
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备注/Memo

备注/Memo:
基金项目：总参“十二五”医药卫生基金项目（ZCWS14C26）
更新日期/Last Update: 2017-07-20