|本期目录/Table of Contents|

[1]屈敏.复发多发性骨髓瘤患者预后因素分析[J].医学研究与战创伤救治(原医学研究生学报),2017,19(04):376-379.[doi:10.3969/j.issn.1672-271X.2017.04.011]
 QU Min.Analysis of prognostic factors of patients with multiple myeloma recrudescence[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2017,19(04):376-379.[doi:10.3969/j.issn.1672-271X.2017.04.011]
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复发多发性骨髓瘤患者预后因素分析()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第19卷
期数:
2017年04期
页码:
376-379
栏目:
出版日期:
2017-08-10

文章信息/Info

Title:
Analysis of prognostic factors of patients with multiple myeloma recrudescence
作者:
屈敏
作者单位:617023攀枝花,攀钢集团总医院血液肿瘤科
Author(s):
QU Min
(Department of Hematological-oncology, General Hospital of Panzhihua Iron and Steel Group,Panzhihua 617023,Sichuan,China)
关键词:
多发性骨髓瘤复发骨髓浆细胞骨病分级预后
Keywords:
Multiple myeloma Recurrence Bone marrow plasma cells Bone disease classification Prognosis
分类号:
R733.3
DOI:
10.3969/j.issn.1672-271X.2017.04.011
文献标志码:
A
摘要:
目的 探讨复发多发性骨髓瘤患者预后的影响因素。方法 选取48例复发多发性骨髓瘤患者,在患者入院时收集患者的性别、年龄等临床资料,并在患者治疗后收集患者的实验室、影像学检查结果 ,计算出患者的生存期。结果 血红蛋白、血清白蛋白、骨髓浆细胞、血肌酐、血沉和骨病分级与复发多发性骨髓瘤患者的预后密切相关,差异具有统计学意义(P<0.05)。复发多发性骨髓瘤患者预后的logistic多因素回归分析中,骨髓浆细胞、骨病分级是复发骨髓瘤患者预后的独立因素。结论 骨髓浆细胞和骨病分级是影响复发多发性骨髓瘤患者预后的独立因素。
Abstract:
Objective To investigate the prognostic factors of patients with multiple myeloma recrudescence.Methods 48 patients with recurrent multiple myeloma were selected in the hospital, and the clinical data of patients were collected after patients were admitted, such as gender, age, et al. After the different treatment, laboratory and imaging examination Results were also collected, and the overall survival of patients were calculated.Results Hemoglobin, serum albumin, bone marrow plasma cells, serum creatinine, ESR and bone disease classification were closely related with the prognosis of patients with recurrence multiple myeloma, and the difference was statistically significant (P<0.05). In the logistic multivariate regression analysis of prognostic factors in patients with recurrence multiple myeloma, bone marrow plasma cells and bone disease classification were the independent prognostic factors of patients with recurrence multiple myeloma.Conclusion Bone marrow plasma cells and bone disease classification are the independent prognostic factors of patients with recurrence multiple myeloma.

参考文献/References:

[1]洪铁艳, 余正平. 来那度胺联合地塞米松方案对复发难治多发性骨髓瘤的治疗作用并文献复习[J]. 东南国防医药, 2014, 16(6): 597-599.
[2]陆敏秋, 褚彬, 李真, 等. 多发性骨髓瘤老年患者化疗后感染因素分析与对预后的影响[J]. 中华医院感染学杂志, 2015, 25(22): 5186-5188.
[3]Kumar SK, Rajkumar SV, Dispenzieri A, et al. Improved survival in multiple myeloma and the impact of novel therapies[J]. Blood, 2008, 111(5): 2516-2520.
[4]黄春晖. 硼替佐米及沙利度胺联合 VAD方案治疗难治复发性多发性骨髓瘤疗效观察[J]. 临床血液学杂志, 2010,23 (1): 36-37.
[5]陈文明. 复发难治性多发性骨髓瘤的治疗:《中国多发性骨髓瘤诊治指南(2015年修订)》解读[J]. 中华内科杂志, 2016, 55(2): 93-94.
[6]李春霞, 丁小崇, 孙慧. 硼替佐米联合地塞米松与VAD方案治疗多发性骨髓瘤疗效比较[J]. 中国实用医刊, 2013, 40(5): 28-30.
[7]阚随随, 刘春水, 刘志何, 等. 25例初诊伴髓外浸润的多发性骨髓瘤临床分析[J]. 中国实验诊断学, 2015, 19(4): 672-674.
[8]张海波, 薛华丹, 李烁. 多发性骨髓瘤的影像学进展及临床意义[J]. 中国医学科学院学报, 2014, 36(6): 671-674.
[9]黄艳, 马付坚, 黄枝宁, 等. 多发性骨髓瘤骨病89例临床分析[J]. 重庆医学, 2013, 42(22): 2651-2653.
[10]夏祖耀, 杨惠娟, 陈宝安. 多发性骨髓瘤骨病治疗研究进展[J]. 中国实验血液学杂志, 2016, 24(1): 275-278.
[11]惠双, 王博, 王媛, 等. 沙利度胺联合VAD治疗老年多发性骨髓瘤患者的临床疗效及不良反应[J]. 中国生化药物杂志, 2014, 34(2):90-91,94.
[12]刘增慧,李勇华,肖扬.CD4+CD25+调节性T细胞在骨髓造血系统疾病中的研究进展[J]. 医学研究生学报,2011,24(1):87-91.
[13]麦玉洁, 李睿, 邹德慧, 等. 206例多发性骨髓瘤患者不同方案疗效分析[J]. 中华血液学杂志, 2005, 26(4): 193-196.
[14]陆敏秋, 褚彬, 白砚霞, 等. 多发性骨髓瘤预后的影响因素研究[J]. 中国全科医学, 2016, 19(6): 658-665.
[15]梁赜隐, 任汉云, 岑溪南, 等. 硼替佐米为基础的化疗方案治疗多发性骨髓瘤患者的疗效及预后因素分析[J]. 中华血液学杂志, 2014, 35(3): 225-230.
[16]肖萌, 何娟, 李艳, 等. BD方案与VAD方案治疗多发性骨髓瘤的疗效比较[J]. 中国医科大学学报, 2011, 40(4): 352-356.

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更新日期/Last Update: 2017-07-20