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[1]钟玲,韩忠政,陈凤莉,等.内镜下磁压榨胃肠造瘘应用于动物模型的探讨[J].医学研究与战创伤救治(原医学研究生学报),2018,20(01):18-21.[doi:10.3969/j.issn.1672-271X.2018.01.004]
　ZHONG Ling,HAN Zhong-zheng,CHEN Feng-li,et al.A study for application of endoscopic magnetic compression gastrointestinal anastomosis in animal model[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2018,20(01):18-21.[doi:10.3969/j.issn.1672-271X.2018.01.004]
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内镜下磁压榨胃肠造瘘应用于动物模型的探讨()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年01期
页码:
18-21
栏目:
出版日期:
2018-01-22

文章信息/Info

Title:
A study for application of endoscopic magnetic compression gastrointestinal anastomosis in animal model
作者:
钟玲; 韩忠政; 陈凤莉; 陈钟; 关富; 肖尧生; 张依枫; 张鸣青
作者单位：363000漳州，解放军第175医院(厦门大学附属东南医院) 消化内科(钟玲、韩忠政、陈凤莉、陈钟、关富、肖尧生、张依枫、张鸣青)
Author(s):
ZHONG Ling; HAN Zhong-zheng; CHEN Feng-li; CHEN Zhong; GUAN Fu; XIAO Yao-sheng; ZHANG Yi-feng; ZHANG Ming-qing
(Department of Gastroenterology，the Affiliated Southeast Hospital of Xiamen University/the 175th Hospital of PLA，Digestive Endoscopy Center of Nanjing Military Command，Zhangzhou 363000，Fujian，China)
关键词:
磁压榨; 胃肠造瘘; 动物模型
Keywords:
magnetic compression;  gastrointestinal anastomosis;  animal model
分类号:
R656
DOI:
10.3969/j.issn.1672-271X.2018.01.004
文献标志码:
A
摘要:
目的 内镜下将磁压榨技术应用于比格犬为动物模型行胃肠造瘘术，对其操作技术进行探讨。方法 采用经口内镜下引入环形母磁铁至比格犬空肠，在X线下确定母磁铁位置，然后根据位置于相对应的腹壁外放置一磁力更大的方形磁铁，使腹壁外磁铁锚定母磁铁后，退出胃镜，同样方法 内镜下引入子磁铁于胃内，在X线下确定母磁铁，移去锚定磁铁，使子磁铁尽可能靠近母磁铁，胃腔及肠腔的磁铁相互吸引，并采用X线进一步证实两者相互吸引吻合。结果 内镜下以比格犬为实验动物模型成功完成胃空肠造瘘术。分别于术后第3天、术后1周复查胃镜，造瘘口通畅性良好，磁铁于术后第8天完整排出体外。结论 内镜下磁压榨胃肠造瘘可行、安全有效，创伤小，但操作过程中受磁场干扰大，需设计出更有利于传送释放磁铁且不干扰手术操作的系统装置。
Abstract:
Objective To discuss endoscopic magnetic compression technology applied in Beagle dogs for animal model of gastrointestinal nastomosis.Methods In this experiment, ring mother magnet was introduced to jejunum by peroral endoscopic and was identified the location through X-ray. Then according to the location which was corresponded to abdominal wall, a strong square magnet WAS was placed to anchor the mother magnet. With the same method, a sub-magnet was introduced by endoscopic in the stomach, using the X-ray identified the location of the mother magnet. Then the anchor magnet was removed so that the sub-magnet was as close as possible to the mother magnet, and also stomach magnet and intestine magnet were attracted to each other.Results In the endoscopy, gastrointestinal nastomosis on the Beagle dogs for animal model was successfully completed. It was found that gastrointestinal anastomosis had a good patency by endoscopy 3 days and a week after operation. The magnets were completely excluded from the body 8 days after operation.Conclusion Endoscopic magnetic compression technology is suitable, safe, minimally invasive and effective. But the technology can be influenced largely by magnetic disturbance in the operation. So it is necessary to design a system device which is more advantageous for transmitting the release magnet without interfering with the operation.

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备注/Memo

备注/Memo:
基金项目：南京军区医学科技创新重点项目（15ZD026）；福建省中医药大学校管课题（XB2015077）；吴阶平医学基金会临床科研专项资助项目（320.6750.15231）
更新日期/Last Update: 2018-01-20