|本期目录/Table of Contents|

[1]蔡鑫,梁婷,罗岳西.α-烯醇化酶在肿瘤发生发展中的作用机制研究进展[J].医学研究与战创伤救治(原医学研究生学报),2021,23(01):50-53.[doi:10.3969/j.issn.1672-271X.2021.01.001]
　CAI Xin,LIANG Ting,LUO Yue-xi.Research progress on the role and mechanism of alpha-enolase in tumorigenesis and development[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(01):50-53.[doi:10.3969/j.issn.1672-271X.2021.01.001]
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α-烯醇化酶在肿瘤发生发展中的作用机制研究进展()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年01期
页码:
50-53
栏目:
综述
出版日期:
2021-01-20

文章信息/Info

Title:
Research progress on the role and mechanism of alpha-enolase in tumorigenesis and development
作者:
蔡鑫; 梁婷; 罗岳西
作者单位：637000南充，川北医学院第二临床医学院（南充市中心医院）妇产科（蔡鑫、梁婷、罗岳西）
Author(s):
CAI Xin;  LIANG Ting ;  LUO Yue-xi
(Department of Obstetrics and Gynecology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College，Nanchong 637000, Sichuan, China)
关键词:
α-烯醇化酶; 肿瘤; 上皮间质转化; 侵袭; 转移
Keywords:
alpha-enolase;  tumor;  epithelial-mesenchymal transition;  invasion;  migration
分类号:
R73
DOI:
10.3969/j.issn.1672-271X.2021.01.001
文献标志码:
A
摘要:
肿瘤的发生、发展是一个多基因、多因素、多阶段相互作用的结果。α-烯醇化酶(ENO1)是一种多功能酶，参与多种生理及病理过程，尤其与肿瘤的发生、发展密切相关。研究已证实，ENO1在多种恶性肿瘤中均有不同程度的表达上调，并阐明了部分可能的分子机制。因此，ENO1有望成为一些肿瘤的早期诊断、判断预后的潜在生物标志物和新的治疗靶点。文章主要就ENO1在肿瘤发生发展中的作用及其相关机制的研究进行综述。
Abstract:
The occurrence and development of tumors are the product of a multi-gene, multi-factor, multi-stage interaction. Alpha-enolase (ENO1) is a multifunctional enzyme that participates in various physiological and pathological processes, especially closely associated with the genesis and development of tumors. Studies have confirmed that ENO1 is up-regulated in various malignancies to vary degrees, and some possible molecular mechanisms have been elucidated. In this paper, the research progress of ENO1 in tumor is reviewed, which provides theoretical reference and a basis for further clinical research.

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备注/Memo

备注/Memo:
基金项目：四川省科学技术厅科技计划项目(2016JY0155)；四川省教育厅科研计划项目(16ZA0239)；南充市校科技战略合作项目(18SXHZ0361)
更新日期/Last Update: 2021-01-26