|本期目录/Table of Contents|

[1]王永园,吕磊,李瑶,等.新兵首次长跑训练前后心电图以及氧化应激指标水平对比分析[J].医学研究与战创伤救治(原医学研究生学报),2021,23(03):240-243.[doi:10.3969/j.issn.1672-271X.2021.03.004]
 WANG Yong-yuan,L Lei,LI Yao,et al.Effect of first-time high-intensity exercise on ECG changes and oxidative stress[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(03):240-243.[doi:10.3969/j.issn.1672-271X.2021.03.004]
点击复制

新兵首次长跑训练前后心电图以及氧化应激指标水平对比分析()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年03期
页码:
240-243
栏目:
出版日期:
2021-06-20

文章信息/Info

Title:
Effect of first-time high-intensity exercise on ECG changes and oxidative stress
作者:
王永园吕磊李瑶金涛钟勇
作者单位:210002南京,东部战区总医院(原南京军区总医院)干部心内科(王永园、吕磊、李瑶),健康医学科(金涛、钟勇)
Author(s):
WANG Yong-yuanL LeiLI YaoJIN TaoZHONG Yong
(1.Department of Geriatric Cardiology, 2. Department of Health Medicine, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu, China)
关键词:
运动性心肌损伤心电图氧化应激
Keywords:
exercise-induced myocardial injury ECG oxidative stress
分类号:
R873
DOI:
10.3969/j.issn.1672-271X.2021.03.004
文献标志码:
A
摘要:
目的观察新兵首次高强度训练前后心电图、肌钙蛋白I和氧化应激指标变化,探讨高强度训练对心电图以及氧化应激的影响。方法入组120名新兵战士进行5 km长跑高强度训练,描记训练前以及训练后5 min内心电图,采集训练前以及训练后半小时内静脉血,测定肌钙蛋白I(TnI)、血清超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、丙二醛(MDA)以及一氧化氮(NO),对比分析训练前后各指标的变化。结果与训练前比较,训练后心率(HR)[(65.01±8.68)次/min vs (93.06±10.18)次/min]、Q-Tc间期[(395.95±35.81)ms vs (416.47±26.03)ms]、RV5+SV1振幅[(2.95±0.76)mV vs (3.21±0.83)mV]以及Q-Tc异常的比例(0% vs 8.55%)明显增加,组间差异有统计学意义(P<0.05)。运动后P-R间期以及异常比例、QRS时间及异常比例、心电轴以及异常比例、RV5+SV1振幅异常比例、TnI水平与训练前比较差异无统计学意义(P>0.05)。训练后血清CAT活力[(13.92±7.60)U/mL]较训练前[10.10±4.76 U/mL]明显增加(P<0.05),而SOD活力、MDA较训练前有所增加,NO含量较训练前减少,但差异无统计学意义(P>0.05)。结论高强度训练对新兵心电图变化有影响,可提高机体氧化应激水平。
Abstract:
ObjectiveTo analyze the changes of ECG and oxidative stress after first-time high-intensity training so as to explore the impact of high-intensity training on oxidative stress and the effect on ECG.Methods120 recruits had their first-time 5 km running-training, tracing the ECG before training and within 5 minutes after training, collecting venous blood before training and within half an hour after training, measuring troponin I (TnI), serum superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA) and a Nitrogen oxide (NO), comparative analysis of changes before and after training.ResultsCompared with before training, the HR [(65.01±8.68)bpm vs (93.06±10.18)bpm], Q-Tc [(395.95±35.81)ms vs (416.47±26.03)ms], RV5+SV1 value [(2.95±0.76)mV vs (3.21±0.83)mV] and proportion of Q-Tc abnormal (0% vs 8.55%) are significantly raised(P<0.05). After 30 minutes of training, the activity of serum CAT [(13.92±7.60)U/mL] was significantly increased than that before training [(10.10±4.76)U/mL,P<0.05]. The level of SOD,MDA was raised and NO was decreased after training, but there was no significantdifference(P>0.05).ConclusionHigh-intensity training has an effect on the recruits’ ECG changes, which can improve the oxidative stress level.

参考文献/References:

[1]平政,曹雪滨.运动性心脏损伤的防治与机制研究进展[J].解放军医药杂志, 2018,30(2):110-113.
[2]常芸.运动性心律失常研究现状与展望[J].中国运动医学杂志,2015,34(1):59-68.
[3]陈金良,张晶,卢凡,等.新兵5km越野跑训练致心电图改变426例分析[J].心血管康复医学杂志,2016,25(2):115-118.
[4]吴学宁,张招,王江涛,等.某高海拔训练基地参训官兵高强度运动后心电图评分变化及其与症状自评量表评分的相关性分析[J].解放军医药杂志,2016,28(1):15-18.
[5]Walsh B, Macfarlane PW, Prutkin JM, et al. Distinctive ECG patterns in healthy black adults[J]. J Electrocardiol, 2019,56:15-23.
[6]席晓萍,李莉,金海英.高强度体能训练者心电图特征[J].武警医学,2008,19(12):1130-1132.
[7]Delise P. Abnormal ECG findings in athletes[J]. G Ital Cardiol (Rome), 2019, 20(4):242-253.
[8]Sharma S, Drezner JA, Baggish A, et al. International recommendations for electrocardiographic interpretation in athletes[J]. Eur Heart J,2018,39(16):1466-1480.
[9]Vincent L, Maria T, Paul D, et al. Exercise-induced cardiac troponin I increase and incident mortality and cardiovascular events[J]. Circulation,2019,140(10):804-814.
[10]刘杨,吴志峰. 运动性心肌微损伤的研究现状[J]. 东南国防医药,2014,16(4):401-403.
[11]Gomez-Cabrera MC, Domenech E, Via J. Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training[J]. Free Radic Biol Med,2008,44(2): 126-131.
[12]Lokanatha V,Subramanyam D,Rajendra W. Role of free radicals and antioxidants in gynecological cancers: current status and future prospects[J]. Oxid Antioxid Med Sci,2014,3(1):15-26.
[13]Moukette BM, Pieme CA, Njimou JR, et al. In vitro antioxidant properties, free radicals scavenging activities of extracts and polyphenol composition of a non-timber forest product used as spice: Monodoramyristica[J]. Biol Res,2015,48(1):15.
[14]Michalis GN, Athanasios ZJ. Blood as a reactive species generator and redox status regulator duringexercise[J]. Arch Biochem Biophys,2009,490(2):77-84.
[15]陈志刚,吴立红,董茂生,等.穴位电疗法对一次性高强度军训士兵血清SOD和MDA的影响[J].上海针灸杂志,2014,33(4):328-329.
[16]公雪,李晓燕,张红明.运动预适应对急性运动性损伤后心肌组织氧化应激及凋亡的影响[J].国际心血管病杂志,2017,44(2):46-50.

相似文献/References:

[1]朱春林,李 萍.妊娠中晚期537例心电图分析[J].医学研究与战创伤救治(原医学研究生学报),2009,11(03):243.
[2]刘万林,常永和,鞠云枫,等.急性下壁心肌梗死62例临床分析[J].医学研究与战创伤救治(原医学研究生学报),2008,10(02):133.
[3]王玉占,刘娟.心电图参数预测心脏再同步治疗患者发生超反应的意义[J].医学研究与战创伤救治(原医学研究生学报),2017,19(01):62.[doi:10.3969/j.issn.1672-271X.2017.01.017]
 WANG Yu-zhan,LIU Juan.Electrocardiographic parameters predict super-response in cardiac resynchronization therapy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2017,19(03):62.[doi:10.3969/j.issn.1672-271X.2017.01.017]
[4]李瑶,钟勇,王永园,等.运动习惯对新兵首次高强度训练后心肌损伤的影响[J].医学研究与战创伤救治(原医学研究生学报),2021,23(6):561.[doi:10.3969/j.issn.1672-271X.2021.06.001]
 LI Yao,ZHONG Yong,WANG Yong-yuan,et al.Effect of exercise habits on the myocardial injury of recruits after the first-time high-intensity training[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(03):561.[doi:10.3969/j.issn.1672-271X.2021.06.001]

备注/Memo

备注/Memo:
基金项目:军委后勤保障部卫生局保健专项课题(18BJZ13);中国博士后科学基金(2018M633765)
更新日期/Last Update: 2021-06-17