|本期目录/Table of Contents|

[1]谢溦,王东.脑室出血外引流术后颅内感染的危险因素分析[J].医学研究与战创伤救治(原医学研究生学报),2023,25(2):151-155.[doi:10.3969/j.issn.1672-271X.2023.02.008]
　XIE Wei,WANG Dong.Risk factors of intracranial infection after external drainage for ventricular hemorrhage[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2023,25(2):151-155.[doi:10.3969/j.issn.1672-271X.2023.02.008]
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脑室出血外引流术后颅内感染的危险因素分析()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第25卷
期数:
2023年2期
页码:
151-155
栏目:
临床研究
出版日期:
2023-05-31

文章信息/Info

Title:
Risk factors of intracranial infection after external drainage for ventricular hemorrhage
作者:
谢溦; 王东
作者单位：211100南京，南京医科大学附属江宁医院神经外科（谢溦、王东）
Author(s):
XIE Wei;  WANG Dong
(Department of Neurosurgery,The Jiangning Affiliated Hospital of Nanjing Medical University, Nanjing 211100, Jiangsu,China)
关键词:
脑室出血; 脑室外引流; 颅内感染; 危险因素
Keywords:
intraventricular hemorrhage;  external ventricular drainage;  intracranial infection;  risk factors
分类号:
R651.1
DOI:
10.3969/j.issn.1672-271X.2023.02.008
文献标志码:
A
摘要:
目的探究脑室出血行脑室外引流术后颅内感染的危险因素，为预防脑室出血外引流术后继发颅内感染提供参考。方法对某医院脑室出血后行脑室外引流术的80例患者进行回顾性分析，采用单因素分析和Logistic多元回归分析筛选出继发颅内感染的危险因素。结果本组病例共感染21例，感染率为26%。单因素分析显示：术前GCS评分≤8分、双侧脑室外引流、直接切口处固定引流管、切口脑脊液漏、尿激酶灌注、脑脊液取样是脑室出血外引流术后继发颅内感染的相关危险因素（P<0.05）。Logistic多元回归分析表明术前GCS评分≤8分、尿激酶灌注和脑脊液取样是脑室出血外引流术后继发颅内感染的危险因素（P<0.05）。结论脑室出血外引流术后继发颅内感染受多种因素影响，GCS评分较低的患者需急诊手术，严格无菌操作以及准确把握尿激酶灌注和脑脊液取样指征有助于减少术后颅内感染的发生。
Abstract:
ObjectiveTo study the risk factors for intracranial infection after external ventricular drainage, which can provide reference for preventing intracranial infection after external drainage of intraventricular hemorrhage (IVH).MethodsA retrospective analysis was made on 80 patients with IVH who underwent external ventricular drainage, using single factor analysis and logistic regression to screen risk factors of intracranial infection after external ventricular drainage.ResultsTwenty one cases were infected in this group and the rate of infection was 26%. Single factor analysis showed that preoperative GCS score≤8; bilateral external ventricular drainage; fix the drainage tube at the direct incision; incision leakage of CSF; urokinase perfusion; CSF sampling were the related risk factors of intracranial infection after external drainage of ventricular hemorrhage (P<0.05). Multivariate logistic regression analysis showed that preoperative GCS score≤8, urokinase perfusion and CSF sampling were risk factors for secondary intracranial infection after external drainage of IVH (P<0.05). ConclusionThe secondary intracranial infection after external drainage of IVH is affected by multiple factors. Patients with a low GCS score are required emergency surgery, strict aseptic operation and accurate indication of urokinase perfusion as well as cerebrospinal fluid, which are helpful to reduce postoperative intracranial infection.

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备注/Memo

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更新日期/Last Update: 2023-07-24