|本期目录/Table of Contents|

[1]何小芳,周敏,熊朝月,等.乳腺癌超声征象及其术后复发的危险因素分析[J].医学研究与战创伤救治(原医学研究生学报),2022,24(3):274-277.[doi:10.3969/j.issn.1672-271X.2022.03.011]
 HE Xiao-fang,ZHOU Min,XIONG Chao-yue,et al.Ultrasonicsigns of breast cancer and analysis of risk factors for postoperative recurrence[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2022,24(3):274-277.[doi:10.3969/j.issn.1672-271X.2022.03.011]
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乳腺癌超声征象及其术后复发的危险因素分析()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第24卷
期数:
2022年3期
页码:
274-277
栏目:
临床研究
出版日期:
2022-06-30

文章信息/Info

Title:
Ultrasonicsigns of breast cancer and analysis of risk factors for postoperative recurrence
作者:
何小芳周敏熊朝月周海兰朱峰
作者单位:215200苏州,苏州市第九人民医院超声科(何小芳、周敏、熊朝月、周海兰、朱峰)
Author(s):
HE Xiao-fang ZHOU Min XIONG Chao-yue ZHOU Hai-lan ZHU Feng
(Department of Ultrasound,Suzhou Ninth People’s Hospital,Soochow 215200,Jiangsu,China)
关键词:
乳腺癌超声术后复发危险因素
Keywords:
breast cancer ultrasound postoperative recurrence risk factors
分类号:
R445.1;R737.9
DOI:
10.3969/j.issn.1672-271X.2022.03.011
文献标志码:
A
摘要:
目的探讨乳腺癌超声征象及其术后复发的危险因素。方法回顾性分析2018年1月至2019年6月在苏州市第九人民医院接受根治性手术治疗的女性乳腺癌患者174例(共188个乳腺原发性癌灶)的临床资料。根据患者术后随访是否复发分为复发组和非复发组,比较2组乳腺超声征像,采用Logistic回归分析乳腺癌超声征像在患者术后复发中的影响状况。结果174例患者术后随访中,6例失访(共7个乳腺原发性癌灶),50例复发共54个乳腺原发性癌灶(复发组),占比29.83%(54/181)。复发组与非复发组在肿瘤最大直径、边缘、纵横比、钙化、Alder血流分级方面的比较,差异有统计学意义(P<0.05)。Logistic回归分析显示肿瘤直径≥3 cm(OR=1.514,95%CI:1.257~3.209)、边缘模糊(OR=3.497,95%CI:1.926~5.473) 、纵横比>1(OR=1.718,95%CI:1.148~4.376)、钙化(OR=1.872,95%CI:1.162~2.894)、Alder血流Ⅱ~Ⅲ级(OR=1.404,95%CI: 1.053~2.617)均是乳腺癌术后复发的危险因素(P<0.05)。结论肿瘤直径≥3 cm、肿瘤边缘模糊、纵横比>1、肿瘤内钙化、Alder血流Ⅱ~Ⅲ级的乳腺癌患者术后复发风险较高。
Abstract:
ObjectiveTo explore the ultrasound signs of breast cancer and the risk factors for postoperative recurrence.MethodsA total of 188 primary breast cancer foci of 174 female breast cancer patients who received radical surgery in Suzhou Ninth People’s Hospital from January 2018 to June 2019 were selected as the research objects. Patients were divided into recurrence group and non-recurrence group according to the postoperative follow-up. Compared the two groups of breast ultrasound signs, logistic regression was used to analyze the influence of breast cancer ultrasound signs in patients with postoperative recurrence.ResultsDuring the follow-up of 174 patients, 6 cases were lost to follow-up (a total of 7 primary breast cancer foci). A total of 54 primary breast cancer foci in 50 cases of recurrence (recurrence group) accounted for 29.83% (54/181). The comparison between the recurring group and the non-recurring group in terms of tumor maximum diameter, margin, aspect ratio, calcification, and Alder blood flow classification was significantly different (P<0.05). Logistic regression analysis showed that tumor diameter ≥ 3 cm (OR=1.514, 95%CI: 1.257-3.209), blurred edges (OR=3.497, 95%CI: 1.926-5.473), aspect ratio> 1 (OR=1.718, 95%CI: 1.148-4.376), calcification (OR=1.872, 95%CI: 1.162-2.894), Alder blood flow grade Ⅱ-Ⅲ (OR=1.404, 95%CI: 1.053-2.617) were the risk of breast cancer recurrence after surgery factors (P<0.05).ConclusionBreast cancer patients with tumor diameter ≥3 cm, tumor margins fuzzy, aspect ratio >1, intratumoral calcification, Alder blood flow grade Ⅱ to Ⅲ breast cancer patients have a higher risk of postoperative recurrence.

参考文献/References:

[1]张海见,米拉·也尔兰,冷晓玲.乳腺癌超声征象与肿瘤干细胞及上皮间质转化标志物表达水平的相关性[J]. 分子影像学杂志,2021,44(4):624-631.
[2]杨韵贤,李世梅,姚继祎,等.乳腺癌肿物的超声特点与术后复发的Logistic回归分析[J]. 中国超声医学杂志,2021,37(5):509-512.
[3]庄静,王奕萍,张婷,等.多模态超声对乳腺非肿块样病变的诊断价值[J]. 医学研究生学报,2022,35(3):300-302.
[4]栾云,许华宁,吴意赟,等.超声造影对提高乳腺肿块系统分类准确性的价值评估[J]. 东南国防医药,2018,20(5):511-514.
[5]来炳岩,樊健敏.动态增强MRI、超声与钼靶对乳腺良、恶性病灶的诊断价值对比[J]. 中国CT和MRI杂志,2021,19(9):83-85.
[6]张宝方,黄穗,李少英,等.乳腺癌患者HFUS图像与Ki-67、Her-2、PR、ER表达的相关性[J]. 海南医学,2021,32(15):1934-1938.
[7]梅江华.多西他赛联合卡培他滨治疗蒽环类化疗失败复发转移性乳腺癌的临床疗效[J]. 临床合理用药杂志,2021,14(24):88-90.
[8]张建立,唐历,王伟佳.乳腺癌根治术患者血清肿瘤标志物水平及其与预后的关系[J]. 癌症进展,2020,18(16):1653-1655,1659.
[9]中国抗癌协会乳腺癌专业委员会.中国抗癌协会乳腺癌诊疗指南与规范(2008版)[J]. 中国癌症杂志,2009,19(6):448-474.
[10]张柏林,张倩,Priya GS,等.中国年轻乳腺癌发病危险因素——多中心十年回顾性研究[J]. 中国肿瘤,2015,24(12):1042-1047.
[11]Yilmaz MH, Esen G, Ayarcan Y, et al. The role of US and MR imaging in detecting local chest wall tumor recurrence after mastectomy[J]. Diagn Interv Radiol, 2007, 13(1): 13-18.
[12]张晟,张敏,李春艳,等.乳腺癌根治术局部复发后影响预后的相关因素分析[J]. 中华乳腺病杂志(电子版),2010,4(1):32-41.
[13]Bluthner E, Bednarsch J, Malinowski M, et al. Dynamic liver function is an independent predictor of recurrence-free survival after curative liver resection for HCC-A retrospective cohort study[J]. Int J Surg, 2019, 71(1):56-65.
[14]Yaghjyan L, Colditzh A, Rosenr B, et al. Mammo-graphic breast density and breast cancer risk:Interacions of percent density,absolute dense,and non-dense areas with breast cancer risk factors[J]. Breast Cancer Res Treat,2015,150(1):181-189.
[15]陈燕,张江宇,王丽敏,等.非特殊型浸润性乳腺癌超声征象与分子生物学指标关系分析[J]. 广东医学,2019,40(11):1579-1583.
[16]郭灵敏,谷小玉,李林株,等.Her-2、ER、PR、ki-67与乳腺癌淋巴结转移及病理分级的相关性研究[J]. 新疆医学,2021,51(4):452-454.
[17]地里呼玛尔·吐鲁洪,李欣芳,王少华.HR+/HER2-乳腺癌内分泌治疗的研究进展[J]. 东南国防医药,2021,23(4):387-392.
[18]杨倩,朱庆莉,姜玉新,等.乳腺癌改良根治术后局部胸壁复发的临床特征与超声表现[J]. 中华医学超声杂志(电子版),2013,10(8):656-661.
[19]丁荣波,张海鹏,申李胜男,等.乳腺癌钙化灶与其临床、病理特征和预后关系的研究进展[J]. 吉林大学学报(医学版),2019,45(2):450-456.
[20]Tse GM,Tan PH,Cheung HS,et al. Intermediate to highly suspicious calcification in breast lesions:a radiopathologic correlation[J]. Breast Cancer Res Treat,2008,110 (1) :1-7.
[21]Qi XM, Chen AX, Zhang P, et al. Mammographic calcification can predict outcome in women with breast cancer treated with breast-conserving surgery[J]. Oncol Lett,2017,14 (1) :79-88.
[22]王萌,刘建军,陈蕊.乳腺癌患者高频彩色多普勒超声血流特点及阻力系数的变化[J]. 分子影像学杂志,2021,44(3):467-471.
[23]Watanabe T, Kaoku S, Yamaguchi T, et al. Multicenter prospective study of color Doppler ultrasound for breast masses:utility of our color Doppler method[J]. Ultrasound Med Biol, 2019, 45(6):1367-1379.

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更新日期/Last Update: 2022-06-21