|本期目录/Table of Contents|

[1]王加林,王 猛,杨文娟,等.131I治疗甲状腺功能亢进症合并2型糖尿病101例[J].医学研究与战创伤救治(原医学研究生学报),2011,13(02):109-111.
 WANG Jia-lin,WANG Meng,YANG Wen-juan,et al.Clinical study of 131I on the treatment of 101 cases of hyperthyroidism patients with type 2 diabetes mellitus[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(02):109-111.
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131I治疗甲状腺功能亢进症合并2型糖尿病101例()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年02期
页码:
109-111
栏目:
出版日期:
2011-03-20

文章信息/Info

Title:
Clinical study of 131I on the treatment of 101 cases of hyperthyroidism patients with type 2 diabetes mellitus
文章编号:
1672-271X(2011)02-0109-03
作者:
王加林王 猛杨文娟吴德平周 玮
223001 江苏淮安,解放军82医院内分泌科
Author(s):
WANG Jia-lin WANG MengYANG Wen-juanWU De-pingZHOU Wei
Department of Endocrinology,82 Hospital of PLA, Huaian, Jiangsu 223001, China
关键词:
甲状腺功能亢进症2型糖尿病碘放射性核素甲巯咪唑
Keywords:
hyperthyroidism type 2 diabetes mellitus iodine radioisotope methimazole
分类号:
R581.1
DOI:
-
文献标志码:
A
摘要:
目的 评估甲状腺功能亢进症(甲亢)合并2型糖尿病(T2DM)患者131I治疗的临床疗效。方法 197例甲亢合并T2DM患者随机分为131I治疗组(101例)和甲巯咪唑对照组(96例),治疗1年后比较两组的临床疗效。结果 治疗组的甲亢缓解总有效率88.12%(89/101),明显高于对照组的75.00%(72/96)(P<0.01)。结论 131I治疗甲亢合并T2DM患者疗效优于甲巯咪唑。
Abstract:
Objective To evaluate the therapeutic effect of 131I on hyperthyroidism combined with type 2 diabetes mellitus.Methods Patients with hyperthyroidism combined with type 2 diabetes mellitus divided randomly into 131I group (101 cases) and methimazole group(96 cases).The therapeutic effect was observed and compared after 1 year. Results The total effective rate of 131I group(88.12%) was higher than that of methimazole group(75.00%)(P<0.01) .Conclusion 131I therapy is preferred in the treatment of hyperthyroidism combined with type 2 diabetes mellitus to methimazole.

参考文献/References:

[1]朱禧星.甲状腺功能亢进症[M].北京:人民卫生出版社,2001:946-1155.
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[5]王隆德,蒋作君,余 靖,等.临床诊疗指南核医学分册[M].北京:人民卫生出版社,2006:407-408.
[6]Vondra K,Vrbikova J,Dvorakova K.Thyroid gland diseases in adult patients with diabetes mellitus [J].Minerva Endocrinol,2005,30(4):217-236.
[7]Schroner Z,Lazürova I,Petrovieova J. Autoimmune thyropathies in diabetes[J].Vnitr Lek,2006,52(2):137-143.
[8]白 耀. 甲状腺学基础与临床[M]. 北京:科学技术文献出版社,2004:636.
[9] Kita T,Yokoyama K,Kinuya S,et al. Single dose planning for radioiodine-131 therapy of Graves disease[J].Ann Nucl Med,2004,18(2):151-155.

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备注/Memo

备注/Memo:
南京军区2009年医学科技创新课题(09MB116)
更新日期/Last Update: 2011-03-20